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华西医学  2015 

二级准直器在鼻咽癌容积调强放射治疗计划设计中的应用研究

DOI: 10.7507/1002-0179.20150355, PP. 1235-1238

Keywords: 二级准直器,鼻咽癌,容积调强放射治疗

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Abstract:

目的?比较治疗计划系统二级准直器(MLC)角度选择对容积调强放射治疗(VMAT)计划质量与运行效率的影响,探索治疗计划设计的优化方案。方法?随机选取2013年3月-12月治疗的20例鼻咽癌患者,设定不同的MLC角度,进行同步加量的VMAT逆向计划设计,比较MLC角度对靶区和危及器官剂量分布、机器输出跳数的差异。MLC角度分别设置为0、15、30、45、60°。结果?随着MLC角度增大,靶区适形指数和均匀性指数有变差的趋势,0°和15°计划相对最优,45°和60°计划对危机器官的保护不如其他角度好而且机器跳数明显增加。结论?改变MLC角度对治疗计划会产生明显影响,随MLC角度增加,计划质量与运行效率均有变差的趋势,但是小范围改变MLC角度理论上可以降低漏射线对人体的影响。

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