热性惊厥患儿血清电解质和血糖变化的临床研究

目的　探讨热性惊厥患儿血清电解质和血糖的变化及其临床意义。方法　选取2009年6月－2010年12月儿科住院的呼吸道感染并发热性惊厥患儿38例和呼吸道感染无惊厥患儿42例，分别作为观察组和对照组，测定和比较两组患儿血清电解质和血糖值。结果　观察组血清钠离子浓度为（133.05±1.74）mmol/L、氯离子浓度为（100.37±1.79）mmol/L；对照组血清钠离子浓度为（142.19±1.85）mmol/L、氯离子浓度为（104.57±1.55）mmol/L，差异均有统计学意义（P＜0.01）；观察组和对照组血糖浓度依次为（6.93±0.87）、（5.12±0.55）mmol/L，差异有统计学意义（P＜0.01）。观察组在治疗后的血清钠离子、氯离子浓度分别为（140.89±2.68）、（103.29±1.94）mmol/L，均高于发生惊厥时的浓度（P＜0.01）；观察组在治疗后的血糖浓度为（5.31±0.68）mmol/L，明显低于发生惊厥时，差异有统计学意义（P＜0.01）。结论　婴幼儿发生热性惊厥时存在血钠、血氯水平降低和血糖升高，在热性惊厥患儿的治疗中应纠正血钠水平和高血糖。Objective　Toexploretheclinicalsignificanceofthechangesinserumelectrolytesandbloodglucoseinthechildrenwithfebrileconvulsion.Methods　Thirty-eightchildrenwithrespiratoryinfectioncombinedwithfebrileconvulsionand42childrenwithsinglerespiratoryinfectiondiagnosedbetweenJune2009andDecember2010wereselectedastheobservationgroupandcontrolgroup,respectively.Serumelectrolytesandbloodglucoseconcentrationwereassayedandcomparedbetweenthetwogroups.Results　Theconcentrationsofserumsodiumandchloridewere(133.05±1.74)mmol/Land(100.37±1.79)mmol/Lintheobservationgroup,while(142.19±1.85)and(104.57±1.55)mmol/Linthecontrolgroup;thedifferencesbetweenthetwogroupsweresignificant(P<0.01).Theconcentrationsofbloodglucosewere(6.93±0.87)mmol/Lintheobservationgroupand(5.12±0.55)mmol/Linthecontrolgroup;thedifferencewassignificant(P<0.01).Afterthetreatment,theserumconcentrationsofsodiumandchloridewere(140.89±2.68)and(103.29±1.94)mmol/Lintheobservationgroup,whichwerehigherthanthosebeforetreatment(P<0.01).Aftertreatment,thebloodglucoseconcentrationwas(5.31±0.68）mmol/Lintheobservationgroup,whichwaslowerthanthatbeforethetreatment(P<0.01).Conclusion　Hyponatremia,lowserumchlorineandhyperglycemiaoccurreinthefebrileconvulsioninchildren,whichshouldbecorrectedinthetreatmentoffebrileconvulsion.