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华西医学  2014 

早期胃癌临床病理特征与浸润深度的关系

DOI: 10.7507/1002-0179.20140619, PP. 2050-2054

Keywords: 早期胃癌,临床病理,胃镜,淋巴结转移

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Abstract:

目的 探讨早期胃癌临床病理特征与浸润深度的关系,为早期胃癌个体化治疗的选择提供依据。方法 回顾性分析2008年1月-2013年1月经外科手术及术后病理证实18例早期胃癌患者的临床、病理资料,对其年龄、性别、有无消化道出血、有无幽门螺杆菌感染及肿瘤部位、大小、内镜分型、分化程度与肿瘤浸润深度的关系进行单因素分析。结果 18例早期胃癌患者中,黏膜下层浸润9例,其中淋巴结转移3例;黏膜内癌9例,均无淋巴结转移。病理类型为未分化型9例,其中癌细胞浸润至黏膜下层7例,伴淋巴结转移3例;分化型9例,仅有2例浸润至黏膜下层,但无淋巴结转移。患者性别、年龄、肿瘤部位、大小及有无幽门螺杆菌感染与浸润深度无关(P>0.05),内镜分型为Ⅲ型提示黏膜下浸润可能性大(P<0.05)。结论 内镜下大体分型为Ⅲ型的早期胃癌,因多有黏膜下层的浸润,淋巴结转移率高,不适合内镜下治疗。

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