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华西医学  2014 

循环肿瘤细胞的研究进展及其在宫颈癌的研究前景

DOI: 10.7507/1002-0179.20140115, PP. 374-376

Keywords: 宫颈癌,循环肿瘤细胞,研究进展

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Abstract:

宫颈癌是女性恶性肿瘤中最常见的肿瘤之一。目前,宫颈癌的治疗手段是手术辅以放射治疗(放疗)加化学治疗(化疗),且术后复发率较高。在宫颈癌早期可选用手术治疗,同步放、化疗适合于肿瘤各期;部分患者术后根据病理结果,如有高危因素者可能需要补充放、化疗。但现在尚无可靠的无创性指标来预测该疾病的复发,转移和预后。循环肿瘤细胞(CTCs)是存在于患者外周血循环的肿瘤细胞,是肿瘤发生转移的关键。因此,宫颈癌外周血CTCs的检测将有助于临床工作者制定更加个体化的治疗方案,减少复发和转移,改善患者预后。本文就CTCs的研究进展及在宫颈癌的发展前景作一综述。

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