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华西医学  2015 

三种方法治疗剖宫产瘢痕部位妊娠的疗效比较

DOI: 10.7507/1002-0179.20150256, PP. 895-898

Keywords: 剖宫产瘢痕部位妊娠,子宫动脉化学疗法栓塞术,绞杀胚囊,甲氨喋呤

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Abstract:

目的?探讨比较单纯肌肉注射甲氨蝶呤、胚囊绞杀+注射甲氨蝶呤以及子宫动脉化学疗法(化疗)栓塞术3种方法治疗后进行清宫术治疗剖宫产瘢痕部位妊娠(CSP)的临床疗效。方法?回顾性分析2009年1月-2013年12月住院的208例CSP患者治疗前后的临床资料,分为3组A组72例,采用单纯肌肉注射甲氨蝶呤,B组70例,采用胚囊绞杀+注射甲氨蝶呤,C组66例,采用子宫动脉化疗栓塞术。比较3组患者术前治疗时间间隔、住院时间、清宫术中出血、血β-人绒毛膜促性腺激素(血β-HCG)下降至正常所需时间、住院费用、转经时间的差异。结果?进行C组患者术后清宫的术前治疗时间间隔、住院时间、清宫术中出血、血β-HCG下降至正常时间、转经时间,均优于A组、B组,差异有统计学意义(P<0.05);3组住院费用差异无统计学意义(P>0.05)。结论?子宫动脉化疗栓塞术治疗CSP,具有住院时间短、大出血风险低、患者生育功能易保留、安全、疗效确切的优点,值得临床推广应用。

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