全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...
华西医学  2009 

脑损伤患者凝血功能水平和预后的相关性探讨

, PP. 809-811

Keywords: 脑损伤,凝血功能,相关性

Full-Text   Cite this paper   Add to My Lib

Abstract:

目的探讨脑损伤患者凝血功能水平与颅脑损伤伤情转归的相关性。方法收集70例颅脑损伤患者的临床资料,伤者抽取静脉血2mL,进行凝血功能检测,分析结果与临床资料等分别采用SPSS11.5软件进行χ2检验和logistic回归分析。结果在13例凝血功能异常患者中有5例(38%)伤情加重(较入院时脑内血肿体积增大,迟发性血肿等),明显高于凝血功能正常而伤情加重者(12%,P<0.05);单因素和多因素logistic回归分析提示凝血功能异常时脑损伤伤情加重的危险因素。结论脑创伤后凝血功能异常时颅脑损伤患者伤情加重的危险因素。

References

[1]  SELLADURAI B M, VICKNESWARAN M, DURAISAMY S, et al. Coagulopathy in acute head injury: a study of its role as a prognostic indicator[J]. J Br J Neurosurg,1997,11:398-404.?
[2]  李钢,柯以铨.脑损伤后凝血功能改变的研究进展[J].中华创伤杂志,2003,19(1):57-59.?
[3]  TAKAHASHI H, URANO T, TAKADA Y, et al. Fibrinolytic parameters as an admission prognestic marker of head injury in patients who talk and deteriorate[J]. J Neurosurg,1997,86(5):768-772.[13]高李贵,刘重霄,王卉芳,等.颅脑损伤急性期血浆凝血因子水平的变化[J].西安交通大学学报医学版,2003,24(5):505-506.?
[4]  TAKANASHI Y, SHINONAGA M, KOH E, et al. Coagulation disorders as early predictor of brain injury [J]. No To Shinkei,1996,48(11):1009-1013.?
[5]  GRENANDER A,BREDBACKA S,RYDVALL A,et al.Antithrombin treatment in patients with traumatic brain injury: a pilot study[J]. J Neurosurg Anesthesiol,2001,13(1):49-56.?
[6]  VAN’T VEER C, MANN K G. The regulation of the factor Ⅶ-dependent coagulation pathway: rationale for the effectiveness of recombinant factor Ⅶ a in refractory bleeding disorders[J]. Semin Thromb Hemost,2000,26(4):367-372.?
[7]  ALLEN G A, HOFFMAN M, ROBERTS H R, et al. Recombinant activated factor Ⅶ: its mechanism of action and role in the control of hemorrhage. Can J Anaesth,2002,49:S7-S14.?
[8]  DUTTON R P, MCCUNN M, HYDER M, et al. Factor Ⅶa for correction of craumatic coagulopathy[J]. J Trauma,2004,57(4):709-718.
[9]  TALVING P, BENFIELD R, HADJIZACHARIA P, et al. Coagulopathy in severe traumatic brain injury: a prospective study[J]. J Trauma,2009,66(1):55-62.?
[10]  李银平.急性颅脑损伤后亚低温治疗无临床价值[J].中国危重病急救医学,2001,13(8):459.?
[11]  DRUSKIN M S, DRIJANSK R. Afibrinogenemia with severe head trauma[J]. J Am Med Association,1972,219(6):755.?
[12]  谭宗德,徐延森,程新福,等.脑挫裂伤的临床分型与治疗探讨[J].中国临床神经外科杂志,2003,8(1):16-11.?
[13]  靳怀明,李浩,李志华.颅脑损伤术后迟发性脑缺血性损害及其相关性因素[J].河南外科学杂志,2005,11(1):5-6.?
[14]  VANDER A J, MOORE LG, BREWER G, ?et al?. Effects of high altitude on plasma concentrations of testosterone and pituitary gonadotropins in man[J]. Aviat Space Environ Med,1978,49(2):356-357.?
[15]  SCHERER R U, SPANGEBERG P. Procoagulant actibity in patients with isolated severe head trauma[J]. J Crit Care Med,1998,26(1):149-156.?
[16]  GANDO S, NANZAKI S, KEMMOTSU O. Coagulofibrinolytic changes after head injury are not different from those in trauma patients without head injury[J]. J Trauma,1999,46(3):1070-1076.?
[17]  MAY A K, YOUNG JS, BUTLER K, et al. Coagulopathy in severe closed head injury: is empiric therapy warranted[J] J Am Surg,1997,63(2):233-236.?

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133