Feldman G, Siler T, Prasad N, et al. Efficacy and safety of indacaterol 150 microg once-daily in COPD: a double-blind, randomised, 12-week study[J]. BMC Pulm Med, 2010, 10: 11.
[4]
Barr RG, Bourbeau J, Camargo CA, et al. Tiotropium for stable chronic obstructive pulmonary disease: a meta-analysis[J]. Thorax, 2006, 61(10): 854-862.
[5]
Tashkin DP, Celli B, Senn S, et al. UPLIFT Study Investigators. A 4-year trial of tiotropium in chronic obstructive pulmonary disease[J]. N Engl J Med, 2008, 359(15): 1543-54.
[6]
Molfino NA, Zhang P. A meta-analysis on the efficacy of oral theophylline in patients with stable COPD[J]. Int J Chron Obstruct Pulmon Dis, 2006, 1(3): 261-266.
[7]
Ford PA, Durham AL, Russell RE, et al. Treatment effects of low-dose theophylline combined with an inhaled corticosteroid in COPD[J]. Chest, 2010, 137(6): 1338-1344.
[8]
Agarwal R, Aggarwal AN, Gupta D, et al. Inhaled corticosteroids vs placebo for preventing COPD exacerbations: a systematic review and metaregression of randomized controlled trials[J]. Chest, 2010, 137(2): 318-325.
[9]
Calverley PM, Anderson JA, Celli B, et al. Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease[J]. N Engl J Med, 2007, 356(8): 775-789.
[10]
Pela R, Calcagni-AM, Subiaco S, et al. N-acetylcysteine reduce the exacerbation rate in patients with moderate to server COPD[J]. Respiration, 1999, 66 (6): 495-500.
Stav D, Raz M. Effect of N-acetylcysteine on air trapping in COPD: a randomized placebo-controlled study[J]. Chest, 2009, 136(2): 381-386.
[20]
Kirkil G, Hamdi Muz M, Se？kin D, et al. Antioxidant effect of zinc picolinate in patients with chronic obstructive pulmonary disease[J]. Respir Med. 2008, 102(6): 840-844.
Rubinstein I, Kumar B, Scheriever C. Long-term montelukast therapy in moderate to severe COPD-a preliminary observation[J]. Respir Med, 2004, 98(2): 134-138.
[23]
Calverley PM, Sanchez-Toril F, Mcivor A, et al. Effect of 1-year treatment with roflumilast in severe chronic obstructive pulmonary disease[J]. Am J Respir Crit Care Med, 2007, 176(2): 154-61.
[24]
Dastidar SG, Ray A, Shirumalla R, et al. Pharmacology of a novel, orally active PDE4 inhibitor[J]. Pharmacology, 2009, 83(5): 275-286.
[25]
Poole PJ, Chacko E, Wood-Baker RW, et al. Influenza vaccine for patients with chronic obstructive pulmonary disease[J]. Cochrane Database Syst Rev, 2006, 25(1): CD002733.
[26]
Granger R, Walters J, Poole PJ, et al. Injectable vaccines for preventing pneumococcal infection in patients with chronic obstructive pulmonary disease[J]. Cochrane Databases Syst Rev, 2006, 18(4): CD001390.
[27]
Tandon MK, Phillips M, Waterer G, et al. Oral immunotherapy with inactivated nontypeable Haemophilus influenzae reduces severity of acute exacerbations in severe COPD[J]. Chest, 2010, 137(4): 805-811.
