曲马多超前镇痛对子宫切除术患者术后疼痛和恶心呕吐的影响

【】目的观察曲马多超前镇痛对经腹子宫切除术患者术后疼痛和恶心呕吐的影响。方法2008年11月-2009年5月，40例全身麻醉下行经腹子宫切除术的患者，分为超前镇痛组和对照组（n=20）。超前镇痛组和对照组于麻醉诱导前30min分别静脉注射曲马多（3mg/kg）和生理盐水。术后12、24h，观察Bolus次数和芬太尼的用量，患者疼痛评分及术后恶心呕吐的发生率。结果术后12、24h，曲马多超前镇痛组Bolus次数和芬太尼的用量均小于对照组（P0.05）。结论经腹子宫切除术手术前给予曲马多超前镇痛能够减少术后镇痛药的需要量，且不增加术后恶心呕吐的发生率。？【Abstract】ObjectiveToobservetheeffectsoftramadonlpreemptiveanalgesiaonpostoperativepainandpostoperativenauseaandvomiting(PONV)inpatientswithhysterectomy.MethodsFormNovember2008toMay2009,fourtypatientswhohadundergonehysterectomyweredividedintopreemptiveanalgesia(PA)groupandcontrolgroup,20patientsineach.ThePAandcontrolgroupwereintravenouslyinjectedwithtramadol(3mg/kg)andnormalsalinerespectively.Twelveand24hoursafterhysterectomy,theBolustimes,consumptionoffentanil,painscoreandincidenceofPONVwereobserved.ResultsTwelveand24hoursafterhysterectomy,theBolustimesandconsumptionoffentanilwerebothlowerthanthoseincontrolgroup(P0.05).ConclusionIntravenouslyinjectedwithtramadolbeforehysterectomycanrecducethedosageofanalgesic,anddon′tincreasetheincidenceofPONV.