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华西医学  2011 

乙醛脱氢酶1与肿瘤干细胞相关性研究

, PP. 476-478

Keywords: 乙醛胱氢酶1,肿瘤干细胞,研究

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Abstract:

【】 乙醛脱氢酶(acetaldehydedehydrogenase,ALDH)广泛存在于不同组织中,是一类具有高度氧化活性的胞浆酶类。随着肿瘤干细胞理论的提出,ALHD1被发现为多种肿瘤干细胞的表面标志,在肿瘤的诊断、治疗、判断预后等方面发挥一定作用。现就ALDH1在不同肿瘤的具体作用及在放化疗耐药方面的机制作一综述。

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