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华西医学  2011 

瞬时受体电位香草酸亚型1激动剂在肺缺血再灌注损伤保护中的应用前景

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Keywords: 瞬时受体电位香草酸亚型1,,缺血再灌注损伤

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Abstract:

【】瞬时受体电位香草酸亚型1(transientreceptorpotentialvaniuoed1,TRPV1)是非选择性阳离子通道,可被多种配体及刺激激活。TRPV1在组织缺血再灌注损伤(ischemia-reprefusioninjury,IRI)中的作用已在多个器管中被证实。现就对TRPV1在IRI中的病理生理机制及TRPV1激动剂在肺IRI中的保护作用及应用价值进行综述。

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