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华西医学  2012 

骨关节炎的发病机制及其诊治的研究进展

, PP. 1828-1832

Keywords: 骨关节炎,发病机制,诊断标准,临床治疗

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Abstract:

面对人口的老龄化趋势及人类寿命的延长,骨关节炎(OA)越来越多见。随着对OA发病机制认识的不断深化,研究工作者们从OA危险因素到病理学改变,从分子生物学改变到免疫学改变,多方面、多角度地研究OA的发病机制。而其临床诊断主要依靠症状体征、影像学和实验室检查相结合,治疗方面在早中晚期可以分别通过保守药物治疗和手术治疗缓解疼痛并改善功能。因此,阐明OA的发病机制,将有利于提高对OA的认识及早期诊断,也是指导OA实验研究及临床治疗的理论依据。

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