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华西医学  2012 

生长抑素及其类似物抗肿瘤作用机制研究进展

, PP. 622-625

Keywords: 生长抑素,抑制,肿瘤

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Abstract:

生长抑素(SST)是一种广泛应用于临床的多肽类激素,其对机体几乎所有的生理性内分泌反应均起抑制作用。随着研究的不断深入,其在肿瘤治疗领域的作用越来越受到国内外学者的重视。但SST的抗肿瘤机制尚不清楚,可能通过对肿瘤细胞周期的阻滞,诱导肿瘤细胞凋亡,抑制细胞因子合成与分泌并拮抗其促肿瘤生长作用,抑制肿瘤血管生成,抑制肿瘤细胞黏附及侵袭,提高肿瘤对化学治疗药物的敏感性等途径发挥作用。

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