[ 4 ] Culley DJ, Baxter M, Yukhananov R, et al. The memory effects of general anesthesia persist for weeks in young and aged rats[J]. Anesth Analg, 2003, 96(4): 1004-1009.
[ 7 ] Cibelli M, Fidalgo, AR, Terrando N, et al. Role of interleukin-1beta in postoperative cognitive dysfunction[J]. Ann Neurol, 2010, 68(3): 360-368.
[5]
[ 8 ] Cao XZ, Ma H, Wang JK, et al. Postoperative cognitive deficits and neuroinflammation in the hippocampus triggered by surgical trauma are exacerbated in aged rats[J]. Prog Neuropsychopharmacol Biol Psychiatry, 2010, 34(8): 1426-1432.
[6]
[ 9 ] Perucho J, Rubio I, Casarejos MJ, et al. Anesthesia with isoflurane increases amyloid pathology in mice models of Alzheimer’s disease[J]. J Alzheimers Dis, 2010, 19(4): 1245-1257.
[7]
Wang Y, Sands LP, Vaurio L, et al. The effects of postoperative pain and its man agement on postoperative cognitive dysfunction[J]. Am J Geriatr Psychiatry, 2007, 15(1): 50-59.
[ 3 ] Butterfield NN, Graf P, Ries C, et al. The effect of repeated isoflurane anesthesia on spatial and psychomotor performance in young and aged mice[J]. Anesth Analg, 2004, 98(5): 1305-1311.
