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华西医学  2014 

“5?12”地震后绵阳市新生儿先天性心脏病发病率及危险因素分析

DOI: 10.7507/1002-0179.20140389, PP. 1271-1274

Keywords: 地震,先天性心脏病,发病率,危险因素

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Abstract:

目的 了解绵阳地区“5?12”地震后新生儿先天性心脏病(CHD)发病情况,探索可能的危险因素。方法 采用心脏听诊、呼吸评定、血氧饱和度测定和心脏彩色多普勒超声对绵阳地区2011年12月-2012年12月出生的5536例新生儿行CHD筛查,对确诊病例采用病例对照研究方法进行分析。结果 共筛查出CHD患儿65例,其发病率为11.74‰。发病前3位依次是室间隔缺损、房间隔缺损和动脉导管未闭。CHD发生的可能危险因素依次为CHD家族史、母孕早期感染史、母孕期用药及饮酒史、高龄产妇和父母吸烟史,而父母地震经历史未显示与CHD相关。结论 父母地震经历与CHD的发生无关。孕前加强相关健康知识宣教、避免或减少相关危险因素暴露可降低CHD发病风险。新生儿时期CHD筛查可早期发现CHD,并为后续的随访干预提供宝贵时机,降低病死率,提高患儿生命质量。

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