全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...
华西医学  2014 

昂丹司琼预防术后寒战的效果和安全性的Meta分析

DOI: 10.7507/1002-0179.20140326, PP. 1063-1070

Keywords: 术后寒战,昂丹司琼,Meta分析,随机对照试验

Full-Text   Cite this paper   Add to My Lib

Abstract:

目的 系统评价昂丹司琼预防术后寒战的效果和安全性。方法 根据Cochrane系统评价方法,计算机检索Cochrane图书馆、OVID、EMbase、PubMed、中国期刊全文数据库、中国生物医学文献数据库、维普中文科技期刊数据库、万方等数据库,搜索时限1999年1月-2013年9月,收集与昂丹司琼预防术后寒战相关的随机对照试验(RCT),按纳入和排除标准筛选文献,采用RevMan5.0软件进行Meta分析。结果 共纳入9个RCT,包括665例患者。Meta分析显示手术结束前静脉推注昂丹司琼组比手术结束前静脉推注生理盐水术后寒战发生率低RR=0.32,95%CI(0.24,0.42),P<0.05;术后恶心呕吐发生率手术结束前静脉推注昂丹司琼组比手术结束前静脉推注生理盐水低RR=0.30,95%CI(0.14,0.63),P<0.05,新生儿出生后1minApgar评分、5minApgar评分昂丹司琼组和生理盐水组差异无统计学意义WMD=0.03分,95%CI(?0.02,0.09)分,P=0.26;WMD=?0.02分,95%CI(?0.12,0.08)分,P=0.68。结论 术前静脉推注昂丹司琼能明显降低患者术后寒战的发生率,且明显降低术后恶心呕吐发生率,不良反应少。

References

[1]  [ 2 ] Buggy DJ, Crossley AW. Thermoregulation, mild perioperative hypothermia and postoperative shivering[J]. Br J Anaesth, 2000, 84(5): 615-628.
[2]  [ 3 ] Dal D, Kose A, Honca M, et al. Efficacy of prophylactic ketamine in preventing postoperative shivering[J]. Br J Anaesth, 2005, 95(2): 189-192.
[3]  [ 4 ] Tsai YC, Chu KS. A comparison of tramadol, amitriptyline, and meperidine for postepidural anesthetic shivering in parturients[J]. Anesth Analg, 2001, 93(5): 1288-1292.
[4]  [ 5 ] Sagir O, Gulhas N, Toprak H, et al. Control of shivering during regional anaesthesia: prophylactic ketamine and granisetron[J]. Acta Anaesthesiol Scand, 2007, 51(1): 44-49.
[5]  [ 6 ] Horn EP, Standl T, Sessler D, et al. Physostigmine prevents postanesthetic shivering as does meperidine or clonidine[J]. Anesthesiology, 1998, 88(1): 108-113.
[6]  [ 7 ] 杨冬, 薛富善. 麻醉后寒战及防治[J]. 国外医学?麻醉与复苏分册, 2003, 24(1): 21-23.
[7]  [ 8 ] Higgins JPT, Green S. Assessing risk of bias in included studies[M/OL]//Cochrane handbook for systematic reviews of interventions 5.1.0. [updated March . The Cochrane Collaboration, http://www.cochrane-handbook.org.
[8]  [ 9 ] Kelsaka E, Baris S, Karakaya D, et al. Comparison of ondansetron and meperidine for prevention of shivering in patients undergoing spinal anesthesia[J]. Reg Anesth Pain Med, 2006, 31(1): 40-45.
[9]   Entezari Asl M, Isazadehfar Kh, Akhavanakbari G, et al. The effect of ondansetron in prevention of postoperative shivering after general anesthesia in gynecological surgery[J]. Iran Red Crescent Med J, 2012, 14(5): 316-317.
[10]   Abdollahi MH, Forouzannia SK, Bagherinasab M, et al. The effect of ondansetron and meperedin on preventing shivering after off-pump coronary artery bypass graft[J]. Acta Med Iran, 2012, 50(6): 395-398.
[11]  [ 1 ] Alfonsi P. Postanaesthetic shivering epidemiology, pathophysiology and approaches to prevention and management[J]. Drugs, 2001, 61(15): 2193-2205.
[12]   Robert MP, Buggy DJ. Ondansetron given before induction of anesthesia reduces shivering after general anesthesia[J]. Anesth Analg, 2000, 90(6): 1423-1427.
[13]   Shakya S, Chaturvedi A, Sah BP. Prophylactic low dose ketamine and ondansetron for prevention of shivering during spinal anaesthesia[J]. J Anaesthesiol Clin Pharmacol, 2010, 26(4): 465-469.
[14]   刘德昭, 黄品婕, 陈信芝, 等. 恩丹西酮预防剖宫产产妇寒战的临床观察[J]. 广东医学, 2004, 25(12): 1400-1401.
[15]   曾振平. 昂丹司琼预防剖宫产产妇寒战的临床观察[J]. 实用临床医学, 2007, 8(4): 86-88.
[16]   潘维敏, 臧凤松, 曲元. 恩丹西酮预防椎管内阻滞后寒战的效果[J]. 齐鲁医学杂志, 2001, 16(4): 273-275.
[17]   邹延红, 李铁军, 孙继芬. 恩丹西酮预防经皮肾穿刺取石患者寒战效果观察[J]. 新乡医学院学报, 2007, 24(1): 60-62.
[18]   Hsieh MT, Chueh FY, Lin MT. Magnolol decreases body temperature by reducing 5-hydroxytryptamine release in the rat hypothalamus[J]. Clin Exp Pharmacol Physiol, 1998, 25(10): 813-817.
[19]   Dawson NJ, Malcolm JL. Initiation and inhibition of shivering in the rat: interaction between peripheral and central factors[J]. Clin Exp Pharmacol Physiol, 1982, 9(1): 89-93.

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133