Molina JR, Yang P, Cassivi SD, et al．Non—small cell hng cancer: epi-demiohgy, risk factors, treatment, and survivorship [J]． Mayo Clin Proc, 2008, 83(5)：584-594.
[2]
Soda M, Choi YL, Enomoto M. Identification of the transformingEML4-ALK fusion gene in non-small-cell lung cancer [J]. Nalure,2007, 448(7153): 56I-566.· · 202中国热带医学2015年第15卷第02期China Tropical Medicine,February 2015,Vol.15,No.02
[3]
Inamura K, Takeuchi K, Togashi Y, et al．EMIA. ALK fusion islinked to histological characteristics in a subset of lung cancers [J]. J Thorac Oncol, 2008, 3(1): 13-17.
Minca EC, Portier BP, Wang Z, et al. ALK status testing in non-small cell lung carcinoma: correlation between ultrasensitive IHC and FISH [J]. Mol Diagn 2013,15: 341-346.
[6]
Ying J, Guo L, Qiu T, et al. Diagnostic value of a novelfully automated immunochemistry assay for detection of ALK rearrangement inprimary lung adenocarcinoma [J]. Ann Oncol ,2013,24: 2589-2593.
[7]
Jianya Zhou, Jing Zhao. Accurate and economicalDetection of ALK pos-itive lung adenocarcinoma with semiquantitative immunohistochemical screening [J]. PLoS One,2014 ,9(3): e92828.
[8]
Jinghui Wang, Yiran Cai. Clinical Characteristics and Outcomes of Pa-tients with Primary Lung Adenocarcinoma Harboring ALK Rearrange-ments Detected by FISH, IHC, and RT-PCR [J]. PLoS One,2014 ,9(7): e101551.
[9]
Zhang X,Zhang S,Yang X,et al.Fusion of EMIA and ALK is associated with development of lung adenoearcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression [J]. Mol Cancer, 2010, 9:188．
[10]
Tiseo M,Gelsomino F, Boggiani D, et al. EGFR and EML4 一ALK gene mutations in NSCLC:A case report of erlotinib. Resistant patient with both concomitant mutations [J].Lung Cancer,2010,7l(2):24l-243.
[11]
Shaw AT, Yeap BY, Mino-Kenudson M, et al. Clinical features and outcome of patients with non- small- cell lung cancer who harbor EMIA-ALK [J]. J Clin Oncol,2009,27(26):4247-4253.
[12]
Sun Y, Ren Y, Fang Z, et al.Lung adenocarcinoma from East Asian never-smokers is a disease largely defined by targetable oncogenic mutant kinases [J].J Clin Oncol,2010,28(30):4616.
