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各型急性脑梗死患者超敏C-反应蛋白水平及相关因素分析

, PP. 102-104

Keywords: 急性脑梗死,超敏C-反应蛋白,TOAST分型,动脉粥样硬化

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Abstract:

目的探讨不同TOAST病因学分型急性脑梗死(ACI)患者血清超敏C-反应蛋白(hs-CRP)水平及相关因素的关系。方法ACI住院患者116例,在发病72h之内测定血清hs-CRP的水平及其他生化指标,应用TOAST病因分型分类后,各亚型与30例健康对照者进行对比。结果除其他明确病因型(SOE)因病例少未作分析,其他ACI各亚型血清hs-CRP水平明显高于对照组(PP=0.022)、总胆固醇(TC,r=0.322,P=0.021)、低密度脂蛋白-胆固醇(LDL-C,r=0.358,P=0.011)、糖化血红蛋白(HbA1c,r=0.271,P=0.032)、纤维蛋白原(Fbg,r=0.289,P=0.029)、同型半胱氨酸(Hcy,r=0.301,P=0.023)呈正相关。结论血清hs-CRP水平在不同亚型的ACI明显不同,hs-CRP水平与动脉粥样硬化的发生有一定相关性。

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