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2010年东莞市手足口病病原监测分析

, PP. 82-85

Keywords: 手足口病,EV71,Cox,A16,流行特征,实时荧光PCR

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Abstract:

目的了解东莞市手足口病病原谱构成及其流行特征。方法采用实时荧光PCR检测2010年手足口哨点监测医院上送的标本,应用Excel和SPSS分析。结果380例病原阳性病例中,EV71(占29.47%)所占构成比略高于CoxA16(占24.47%),未分型肠道病毒占46.05%。病原感染构成比无性别差异,以5岁以下人群感染为主(占96.72%)。EV71与CoxA16在0~1岁人群感染构成比最低(各为14.43%与11.34%),在1~5岁人群感染构成比较稳定(占36.13%),6岁后以EV71感染为主(占40.0%);3~7月以EV71与CoxA16流行为主,其中6~7月以EV71为主(约占47.91%);8月后以未分型感染为主,其中10~12月感染构成比最高(占87.50%);各监测点EV71与CoxA16呈交替流行,未分型肠道病毒占较大比例。病例样品检出率较高(达89.41%,380/425),以粪便为主(占87.29%),其检出率明显高于肛拭子(73.08%)。结论东莞市手足口病病原谱构成与流行在人群年龄、时间、地域方面均呈动态变化,以CoxA16伴随EV71流行为主,其它未分型肠道病毒也占相当比重。

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