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2型糖尿病患者γ-谷氨酰转肽酶与C肽的相关性

, PP. 737-739

Keywords: 糖尿病,2型,γ-谷氨酰转肽酶,C肽

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Abstract:

目的探讨2型糖尿病患者空腹C肽及餐后2hC肽与γ-谷氨酰转肽酶(γ-GGT)的相关性。方法选取2012年9月至2013年12月于海南省人民医院内分泌科住院治疗的2型糖尿病患者596例为研究对象。按γ-GGT由低到高四分位间距分组,分别为P0~组(150例)、P25~组(147例)、P50~组(150例)、P75~组(149例),观察各组之间空腹C肽、餐后2hC肽的差异,采用方差分析、Spearman相关分析及多元逐步回归分析了解γ-GGT与C肽的相关性。结果P50~组和P75~组中空腹C肽较P0~及P25~组空腹C肽明显升高(均P<0.05)。P75~组餐后2hC肽较P0~组餐后2hC肽升高(P<0.05)。空腹C肽及餐后2hC肽与γ-GGT呈正相关(P<0.05)。多元逐步回归分析显示病程、BMI、γ-GGT、HDL-C是C肽水平的独立危险因素。结论2型糖尿病患者血清γ-GGT水平与血清C肽水平呈正相关。

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