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胃上皮性肿瘤细胞三维结构的体视学参数的判别分析

, PP. 802-804

Keywords: 胃肿瘤,体视学,定量,诊断

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Abstract:

目的探讨胃的良恶性上皮性肿瘤的三维结构的体视学参数,筛选对其诊断有重要意义的参数。方法收集82例,病例包括胃腺癌55例,胃腺瘤8例,胃腺癌患者癌旁正常胃粘膜19例。石蜡切片,HE染色。每例随机取10个视野,用计算机图像分析技术测试有关细胞核和腺体的体视学参数。结果有关体视学参数所建立的判别函数对胃腺癌和胃腺瘤及正常胃组织的判别准确度分别为97.1%、87.5%和100%;对胃高分化腺癌、中分化腺癌、低分化胃腺癌及正常胃组织的判别准确度分别为53.3%、70%、95%和84.2%。结论三维结构的体视学参数Vvn.epi、Svn.epi、Rsvn、λepi、Vn,epi、Sn,epi、Nvn,epi、Rnp及NLS对胃上皮性肿瘤及其胃腺癌分级的判别和诊断具有重要的价值。

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