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TNF-α与胆管癌侵袭转移的研究进展

, PP. 1140-1143

Keywords: 胆管癌,TNF-α,上皮间质转化

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Abstract:

胆管癌是一种恶性胆管上皮肿瘤,其早期诊断困难,导致胆管癌患者预后差。TNF-α作为一种主要的炎性因子,在很多肿瘤的发生发展中起重要作用。在慢性胆管炎症中能诱导胆管癌的发生发展,并在促进胆管癌侵袭转移中扮演一种总开关角色,本综述分析它与胆管癌的侵袭与转移之间的密切关系,并提示抑制TNF-α对胆管癌治疗及预防具有重要作用。

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