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纯钛表面微量元素协同掺杂仿生复合涂层的制备与表征

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Abstract:

以添加多肽分子和微量元素的改良模拟体液为介质,采用湿化学工艺在碱–热处理的医用钛金属表面快速沉积三元微量元素协同掺杂磷酸钙涂层。测试了试样表面及断面的形貌、相组成以及元素分布。结果表明,在60℃或90℃的改良模拟体液中浸泡30min后,钛金属表面出现无机矿物纳米晶粒成核,在浸泡4h内形成连续、致密的由微量元素硅、锶、锌协同掺杂羟基磷灰石[Ca10(PO4)6(OH)2]和镁白磷钙石[Ca9Mg(PO4)6PO3(OH)]的复合物矿化涂层。这种在60℃或90℃的改良模拟体液中浸泡4h后形成的仿生涂层与钛基底的结合强度分别达到(20.3±1.2)MPa和(24.4±1.6)MPa,均优于在37℃的模拟体液内浸泡14d后制备的涂层结合强度(14.8±1.6)MPa。此外,与仅添加多肽分子的模拟体液中制备的磷酸钙涂层比较,这种新型微量元素掺杂的磷酸钙涂层更能支持骨质疏松症活体动物来源的骨髓间充质干细胞粘附和铺展。

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