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多孔钛支架表面羟基磷灰石的仿生生长

DOI: 10.14062/j.issn.0454-5648.2015.06.19

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Abstract:

以纯钛粉为原料,采用选区激光烧结(SLS)技术制备不同孔隙率仿生人工骨试样。测试烧结试样表面抗压强度,将试样表面处理后,在4倍模拟体液(SBF)中浸泡,利用X射线衍射、扫描电子显微镜和能谱分析表面涂层的物相组成,观察多孔试样的表面、纵切面及孔内涂层形貌,计算表面涂层的钙磷比。讨论了激光扫描速率和扫描间距对试样孔隙率的影响。结果表明SLS可以获得内部连通微孔结构的试样。经过4倍模拟体液中浸泡8d,在2组试样外表面及孔内均产生类骨磷灰石涂层,实现了HA钙磷涂层的三维生长。孔隙率较高的试样抗压强度为117MPa,其表面诱导羟基磷灰石沉积的能力更强,且表面涂层的钙磷比与自然骨更接近,涂层的综合性能更好。

References

[1]  ???? 韩劲. 纳米碳酸羟基磷灰石及其有机复合生物材料的研究[D]. 成都: 四川大学, 2005.
[2]  HAN Jin. Study on nano-carbonated hydroxyapatite and its organic biocomposites (in Chinese dissertation), Chengdu : Sichuan University , 2005.
[3]  ??? LANGER R, VACANTI J P. Tissue engineering[J]. Science, 1993, 260(5110): 920–926.
[4]  ??? HENCH L L, POLAK J M. Third-generation biomedical materials[J]. Science, 2002, 295(5557): 1014–1017.
[5]  ??? JANDT K D. Evolutions, revolutions and trends in biomaterials science: a perspective[J]. Adv Eng Mater, 2007, 9(12): 1035–1050.
[6]  ? 孙浩亮, 郭大刚, 徐可为, 憨勇. 仿生浸泡对磷酸钙骨水泥抗压强度的影响[J]. 硅酸盐学报, 2005, 01: 115–119. SUN Haoliang, GUO Dagang, XU Kewei, et al. J Chin Ceram Soc, 2005, 01: 115–119.
[7]  ? 张涛, 高杰维, 屈树新, 等. 钙磷物质的量比对磷酸钙骨水泥性能的影响[J]. 无机化学学报, 2010, 26(6): 957–962. ZHANG Tao, GAO Jiewei, QU Shuxin, et al. Chin J Inorg Chem (in Chinese), 2010, 26(6): 957–962.
[8]  ??? 胡江. 激光快速成形制备钛表面HA涂层及其成骨相关性能研究[D]. 西安: 第四军医大学, 2011. HU Jiang. Preparation and Biological Performance of HA Coatings Fabricated by Laser Rapid Forming on cp-Ti (in Chinese dissertation), Xi'an : The Fourth Military Medical University, 2011.
[9]  ??? 胡淑慧. 钛合金表面激光熔覆生物陶瓷涂层组织及性能的研究[D].武汉: 华中科技大学, 2012. HU Shuhui. Study on Microstructure and Properties of Bioceramic Coatings by Laser Cladding on the Surface of Titanium Alloy (in Chinese dissertation), Wuhan :Hua Zhong University of Science and Technology, 2012.
[10]  ??? RAU J V, SMIRNOV V V, LAURETI S, et al. Properties of pulsed laser deposited fluorinated hydroxyapatite films on titanium[J]. Mater Res Bull, 2010, 45(9): 1304–1310.
[11]  ??? RABIEI,STEFAN S,MARK R A, et al. Deposition and investigation of functionally graded calcium phosphate coatings on titanium[J]. Acta Biomater, 2009, 5(9): 3563–3572.
[12]  ??? 杨辉, 肖兵娟. 碱处理法制备钛合金表面羟基磷灰石涂层[J]. 硅酸盐通报, 2009, 01: 84–89. YANG Hui, XIAO Bingjuan. Bull Chin Ceram Soc (in Chinese), 2009, 01: 84–89.
[13]  ? VARMA H K, YOKOGAWA Y, ESPINOSA F F. et al. Porous calcium phosphate coating over phosphorylated chiosan fim by a biomimetic method[J]. Biomaterial, 1999(20): 879–884.
[14]  ? JIN Q M, TAKITA H, KOHGO T, et al. Effects of geometry of hydroxyapatite as a cell substratum in bmp-induced ectopic boneformation[J]. Biomed Mater Res, 2000, 52: 491–499.
[15]  ? 李瑞迪. 金属粉末选择性激光熔化成形的关键基础问题研究[D]. 武汉: 华中科技大学, 2010. LI Ruidi. Research on the Key Basic Issues in Selective Laser Melting of Metallic Powder (in Chinese dissertation), Wuhan : Huazhong University of Science and Technology, 2010.
[16]  ? 顾冬冬, 沈以赴, 潘琰峰, 等. 金属粉末选择性激光烧结成形机制的研究[J]. 材料导报, 2004,06: 11–14. GU Dongdong, SHEN Yifu, PAN Yanfeng, et al. Mater Rev (in Chinese), 2004, 06: 11–14.
[17]  ? JIN Q M, TAKITA H, KOHGO T, et al.Effects of geometry of hydroxyapatite as a cell substratum in bmp-induced ectopic boneformation[J]. Biomed Mater Res, 2000, 52: 491–499.
[18]  ??? 王秀鹏, 叶建东, 王迎军. 钙磷摩尔比对新型PCCP+DCPA体系骨水泥性能的影响[J]. 硅酸盐学报, 2007, 35(12): 1582–1586. WANG Xiupeng, YE Jiandong, WANG Yingjun. J Chin Ceram Soc (in Chinese), 2007, 35(12): 1582–1586.

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