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Hadamard变换离子迁移谱的理论模拟初步研究

, PP. 524-529

Keywords: 光谱学,离子迁移谱,Hadamard变换,理论模拟,信噪比

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Abstract:

通过改变采样点数,理论优化了Hadamard变换离子迁移谱(Hadamardtransformionmobilityspectrometry,HT-IMS)谱图的采样速率;通过增加模拟的白噪声,分析了该方法提高谱图信噪比的效果和对分辨率的影响。初步结果表明,在单次离子门门宽0.4ms内,采集8个及以上数据点可以完整地反演IMS谱图;Hadamard变换方法得到的谱图的信噪比是传统IMS谱图信噪比的15.8倍,是相同时间内多次传统IMS谱图平均后信噪比的4.6倍;变换过程对IMS谱图分辨率无明显影响。Hadamard变换IMS的模拟不仅对采样速率等参数的选择和优化提供理论依据,而且为下一步实验控制和反演奠定软件基础。

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