Kümmerer K. Antibiotics in the aquatic environment-A review-Part I[J]. Chemosphere, 2009, 75(4): 417-434
[3]
Richardson B J, Lam P K S, Martin M. Emerging chemicals of concern: Pharmaceuticals and personal care products (PPCPs) in Asia, with particular reference to Southern China[J]. Marine Pollution Bulletin, 2005,50(9):913-920
[4]
Hirsch R, Ternes T, Haberer K, et al. Occurrence of antibiotics in the aquatic environment[J]. The Science of the Total Environment, 1999, 225(1/2):109-118
Halling-S？rensen B, Nors Nielsen S, Lanzky P F, et al. Occurrence, fate and effects of pharmaceutical substances in the environment-A review[J]. Chemosphere, 1998, 36(2): 357-393
Xu W H, Zhang G, Li X D, et al. Occurrence and elimination of antibiotics at four sewage treatment plants in the Pearl River Delta (PRD), South China[J]. Water Research, 2007, 41(19): 4526-4534
[14]
Leung H W, Minh T B, Murphy M B, et al. Distribution, fate and risk assessment of antibiotics in sewage treatment plants in Hong Kong, South China[J]. Environment international, 2012, 42: 1-9
Luo Y, Xu L, Rysz M, et al. Occurrence and transport of tetracycline, sulfonamide, quinolone, and macrolide antibiotics in the Haihe River Basin, China[J]. Environmental science & technology, 2011, 45(5): 1827-1833
[17]
Zheng Q, Zhang R J, Wang Y H, et al. Occurrence and distribution of antibiotics in the Beibu Gulf, China: Impacts of river discharge and aquaculture activities[J]. Marine Environmental Research, 2012, 78: 26-33
[18]
Yang J F, Ying G G, Zhao J L, et al. Spatial and seasonal distribution of selected antibiotics in surface waters of the Pearl Rivers, China[J]. Journal of Environmental Science and Health, Part B, 2011, 46(3): 272-280
Zheng S L, Qiu X Y, Chen B, et al. Antibiotics pollution in Jiulong River estuary: Source, distribution and bacterial resistance[J]. Chemosphere, 2011, 84(11): 1677-1685
[21]
Zhang X, Zhang D D, Zhang H, et al. Occurrence, distribution, and seasonal variation of estrogenic compounds and antibiotic residues in Jiulongjiang River, South China[J]. Environmental Science and Pollution Research, 2012, 19(5): 1392-1404
[22]
Lapworth D J, Baran N, Stuart M E, et al. Emerging organic contaminants in groundwater: A review of sources, fate and occurrence[J]. Environmental pollution, 2012, 163: 287-303
[23]
Zhu Y G, Johnson T A, Su J Q, et al. Diverse and abundant antibiotic resistance genes in Chinese swine farms[J]. Proceedings of the National Academy of Sciences, 2013, 110(9): 3435-3440
[24]
Cleuvers M. Aquatic ecotoxicity of pharmaceuticals including the assessment of combination effects[J]. Toxicology Letters, 2003, 142(3): 185-194
[25]
Liu B Y,Nie X P,Liu W Q,et al. Toxic effects of erythromycin,ciprofloxacin and sulfamethoxazole on photosynthetic apparatus in Selenastrum capricornutum[J]. Ecotoxicology and Environmental Safety,2011, 74(4): 1027-1035
[26]
Halling-S？rensen B, Sengel？v G, Tj？rnelund J. Toxicity of tetracyclines and tetracycline degradation products to environmentally relevant bacteria, including selected tetracycline-resistant bacteria[J]. Archives of Environmental Contamination and Toxicology, 2002, 42(3): 263-271
[27]
Wollenberger L, Halling-S？rensen B, Kusk K O. Acute and chronic toxicity of veterinary antibiotics to Daphnia magna[J]. Chemosphere, 2000, 40(7): 723-730
[28]
Baquero F, Martínez J L, Cantón R. Antibiotics and antibiotic resistance in water environments[J]. Current opinion in biotechnology, 2008, 19(3): 260-265
[29]
Crane M, Watts C, Boucard T. Chronic aquatic environmental risks from exposure to human pharmaceuticals[J]. Science of the Total Environment, 2006, 367(1): 23-41
[30]
Yan C X, Yang Y, Zhou J L, et al. Antibiotics in the surface water of the Yangtze Estuary: Occurrence, distribution and risk assessment[J]. Environmental Pollution, 2013, 175: 22-29
[31]
Jiang L, Hu X L, Yin D Q, et al. Occurrence, distribution and seasonal variation of antibiotics in the Huangpu River, Shanghai, China[J]. Chemosphere, 2011, 82(6): 822-828
Kim S C, Carlson K. Temporal and spatial trends in the occurrence of human and veterinary antibiotics in aqueous and river sediment matrices[J]. Environmental science & technology, 2007, 41(1): 50-57
Zhang H M, Liu P X, Feng Y J, et al. Fate of antibiotics during wastewater treatment and antibiotic distribution in the effluent-receiving waters of the Yellow Sea, northern China[J]. Marine Pollution Bulletin, 2013, 73(1): 282-290
[38]
Gao L H, Shi Y L, Li W H, et al. Occurrence of antibiotics in eight sewage treatment plants in Beijing, China[J]. Chemosphere, 2012, 86(6): 665-671
Zhang R J, Zhang G, Zheng Q, et al. Occurrence and risks of antibiotics in the Laizhou Bay, China: Impacts of river discharge[J]. Ecotoxicology and environmental safety, 2012, 80: 208-215
[41]
Zhang R J, Tang J H, Li J, et al. Antibiotics in the offshore waters of the Bohai Sea and the Yellow Sea in China: Occurrence, distribution and ecological risks[J]. Environmental Pollution, 2013, 174: 71-77
[42]
Zhang D D, Lin L F, Luo Z X, et al. Occurrence of selected antibiotics in Jiulongjiang River in various seasons, South China[J]. Journal of Environmental Monitoring, 2011, 13(7): 1953-1960
[43]
Xu W H, Zhang G, Zou S C, et al. A preliminary investigation on the occurrence and distribution of antibiotics in the Yellow River and its tributaries, China[J]. Water Environment Research, 2009, 81(3): 248-254
[44]
Zou S C, Xu W H, Zhang R J, et al. Occurrence and distribution of antibiotics in coastal water of the Bohai Bay, China: Impacts of river discharge and aquaculture activities[J]. Environmental Pollution, 2011, 159(10): 2913-2920
Organization for Economic Co-operation and Development (OECD). Harmonized integrated hazard classification for human health and environmental effects of chemicals[R]. As endorsed by the 28th Joint Meeting of the Chemicals Committee and the Working Party on Chemicals in November 1998. OECD, Paris
[52]
Li Z H, Randak T. Residual pharmaceutically active compounds (PhACs) in aquatic environment-status, toxicity and kinetics: A review[J]. VeterinarniMedicina, 2009, 54(7): 295-314
[53]
Isidori M, Lavorgna M, Nardelli A, et al. Toxic and genotoxic evaluation of six antibiotics on non-target organisms[J]. Science of the Total Environment, 2005, 346(1): 87-98
[54]
Minagh E, Hernan R, O'Rourke K, et al. Aquatic ecotoxicity of the selective serotonin reuptake inhibitor sertraline hydrochloride in a battery of freshwater test species[J]. Ecotoxicology and Environmental Safety, 2009, 72(2): 434-440
[55]
Ferrari B, Paxeus N, Giudice R L, et al. Ecotoxicological impact of pharmaceuticals found in treated wastewaters: Study of carbamazepine, clofibric acid, and diclofenac[J]. Ecotoxicology and Environmental Safety, 2003, 55(3): 359-370
[56]
Kim Y, Choi K, Jung J, et al. Aquatic toxicity of acetaminophen, carbamazepine, cimetidine, diltiazem and six major sulfonamides, and their potential ecological risks in Korea[J]. Environment International, 2007, 33(3): 370-375
[57]
Halley B A, Jacob T A, Lu A Y H. The environmental impact of the use of ivermectin: Environmental effects and fate[J]. Chemosphere, 1989, 18(7): 1543-1563
[58]
Hutchinson T H, Yokota H, Hagino S, et al. Development of fish tests for endocrine disruptors[J]. Pure and applied chemistry, 2003, 75(11): 2343-2353
[59]
Nakamura Y, Yamamoto H, Sekizawa J, et al. The effects of pH on fluoxetine in Japanese medaka (Oryzias latipes): Acute toxicity in fish larvae and bioaccumulation in juvenile fish[J]. Chemosphere, 2008, 70(5): 865-873
[60]
Huggett D B, Brooks B W, Peterson B, et al. Toxicity of select beta adrenergic receptor-blocking pharmaceuticals (β-blockers) on aquatic organisms[J]. Archives of Environmental Contamination and Toxicology, 2002, 43(2): 229-235
[61]
Jiang L, Lin Z, Hu X, et al. Toxicity prediction of antibiotics on luminescent bacteria, Photobacterium phosphoreum, based on their quantitative structure-activity relationship models[J]. Bulletin of Environmental Contamination and Toxicology, 2010, 85(6): 550-555
