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环境化学  2015 

抗生素抗性基因在废(污)水处理系统的来源、传播扩散、归趋以及污染控制研究进展

Keywords: 抗生素,抗生素抗性基因,污水处理厂

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Abstract:

人类在生活生产中大量使用抗生素,使抗生素抗性菌(Antibioticresistancebacteria,ARB)和抗性基因(Antibioticresistancegenes,ARGs)日益在环境中被检出.含有这些污染物的污水被污水处理系统(Wastewatertreatmentplants,WWTPs)所接纳,抗性细菌在处理系统内得以大量增殖,使得污水处理系统成为抗性细菌和抗性基因的重要储存库.由于污水处理系统对ARB和ARGs的处理效果并不理想,抗性基因随出水排放至纳污水体,会造成环境中抗性基因污染.本文总结并分析了抗生素抗性基因在污水处理系统中的来源、传播扩散途径、归趋以及污染控制的最新研究进展,提出了现存问题以及今后工作的重点,以期为ARGs的污染控制及消减提供可行性参考.

References

[1]  Agers?Y, Petersen A. The tetracycline resistance determinant tet 39 and the sulphonamide resistance gene sulII are common among resistant Acinetobacter spp. isolated from integrated fish farms in Thailand[J]. J Antimicrob Chemother, 2007, 59:23-27
[2]  Heuer H, Kr?gerrecklenfort E, Wellington E M H, et al. Gentamic in resistance genes in environmental bacteria: Prevalence and transfer[J]. FEMS Microbiol Lett, 2002, 42 (2): 289-302
[3]  Borjesson S, Melin S, Matussek A, et al. A seasonal study of the mecA gene and Staphylococcus aureus including methicillin-resistant S. aureus in a municipal wastewater treatment plant[J].Water Research, 2009, 43: 925-932
[4]  Zhang X X, Zhang T. Occurrence, Abundance, and Diversity of Tetracycline Resistance Genes in 15 Sewage Treatment Plants across China and other global locations[J]. Environmental Science & Technology, 2011, 45:2598-2604
[5]  Huang J J, Hu H Y,Lu S Q, et al. Monitoring and evaluation of antibiotic-resistant bacteria at a municipal wastewater treatment plant in China[J]. Environment International, 2011, 42:31-36
[6]  Fuentefria D B, Ferreira A E, Cor?áo G. Antibiotic-resistant Pseudomonas aeruginosa from hospital wastewater and superficial water: Are they genetically related? [J]. Journal of Environmental Management. 2011, 92:250-255
[7]  Duong H A, Pham N H, Nguyen H T. Occurrence, fate and antibiotic resistance of fluoroquinolone antibacterials in hospital wastewaters in Hanoi, Vietnam[J]. Chemosphere, 2008, 72:968-973
[8]  Schwartz T, Kohnen W, Jansen B, et al. Detection of antibiotic-resistant bacteria and their resistance genes in wastewater, surface water, and drinking water biofilms[J]. FEMS Microbiol Ecol, 2003, 43:325-335
[9]  Li J, Wang T, Shao B, et al. Plasmid-mediated quinolone resistance genes and antibiotic residues in wastewater and soil adjacent to swine feedlots: Potential transfer to agricultural lands[J]. Environmental Health Perspectives, 2012, 120(8):1144-1149
[10]  Davison J. Genetic Exchange between Bacteria in the Environment[J]. Plasmid, 1999, 42:73-91
[11]  Ferreira da S M, Tiago I, Verissimo A, et al. Antibiotic resistance of enterococci and related bacteria in an urban waste water treatment plant[J]. FEMS Microbiol Ecol, 2006, 55:322-329
[12]  Kim S, Jensen J N, Aga D S, et al. Tetracycline as a selector for resistant bacteria in activated sludge[J]. Chemosphere, 2007, 66:1643-1651
[13]  Eikmeyer F, Hadiati A, Szczepanowski R. The complete genome sequences of four new IncN plasmids from wastewater treatment plant effluent provide new insights into IncN plasmid diversity and evolution[J]. Plasmid, 2012, 68:13-24
[14]  Iversen A, Kun I, Rahman M, et al. Evidence for transmission between humans and the environment of a nosocomial strain of Enterococcus faecium[J]. Environment Microbiology, 2004, 6:55-59
[15]  Mokracka J, Koczura R, Kaznowski A. Multiresistant Enterobacteriaceae with class 1 and class 2 integrons in a municipal wastewater treatment plant[J]. Water research, 2012, 46:3353 -3363
[16]  Ramsden S J, Ghosh S, Bohl L J. Phenotypic and genotypic analysis of bacteria isolated from three municipal wastewater treatment plants on tetracycline-amended and ciprofloxacin-amended growth media[J]. Journal of Applied Microbiology, 2010, 109:1609-1618
[17]  Kim S, Park H, Chandran K. Propensity of activated sludge to amplify or attenuate tetracycline resistance genes and tetracycline resistant bacteria:A mathematical modeling approach[J]. Chemosphere, 2010, 78(9):1071-1077
[18]  Gao P, Munir M, Xagoraraki I. Correlation of tetracycline and sulfonamide antibiotics with corresponding resistance genes and resistant bacteria in a conventional municipal wastewater treatment plant[J]. Science of the Total Environment, 2012, 421:173-183
[19]  Novo A, Célia M, Manaia. Factors influencing antibiotic resistance burden in municipal wastewater treatment plants[J]. Appl Microbiol Biotechnol, 2010, 87:1157-1166
[20]  Diehl D L, Lapara T M. Effect of temperature on the fate of genes encoding tetracycline resistance and the integrase of class 1 integrons within anaerobic and aerobic digesters treating municipal wastewater solids[J]. Environmental Science & Technology, 2010, 44:9128-9133
[21]  Fan C A, He J Z. Proliferation of antibiotic resistance genes in microbial consortia of sequencing batch reactors (SBRs) upon exposure to trace erythromycin or erythromycin-H2O[J]. Water Research, 2011, 45:3098-3106
[22]  Largus T, Angenent M M, George U, et al. Effect of the presence of the antimicrobial tylosin in swine waste on anaerobic treatment. Water Research, 2008, 42:2377-2384
[23]  Dodd, Michael C. Potential impacts of disinfection processes on elimination and deactivation of antibiotic resistance genes during water and wastewater treatment[J]. Journal of Environmental Monitoring, 2012, 14:1754-1771
[24]  Da Costa M P, Vaz-Pires P, Bernardo F. Antimicrobial resistance in Enterococcus spp. isolated in inflow, effluent and sludge from municipal sewage water treatment plants [J]. Water Research, 2006, 40(8): 1735-1740
[25]  Huang J J, Hu H Y, Tang F. Inactivation and reactivation of antibiotic-resistant bacteria by chlorination in secondary effluents of a municipal wastewater treatment plant[J]. Water Research, 2011, 45:2775-2781
[26]  Shi P, Jia S, Zhang X X. Metagenomic insights into chlorination effects on microbial antibiotic resistance in drinking water[J]. Water Research, 2012, 47(1):111-120
[27]  Ma Y, Wilson C A, Novak J T, et al. Effect of various sludge digestion conditions on sulfonamide, macrolide, and tetracycline resistance genes and class I integrons[J]. Environmental Science & Technology, 2011, 45:7855-7861
[28]  Engemann C A, Adams L, Knapp C W, et al. Disappearance of oxytetracycline resistance genes in aquatic systems[J]. FEMS Microbiol. Lett, 2006, 263(2):176-182
[29]  Pruden A, Arabi M, Storteboom H N. Correlation between upstream human activities and riverine antibiotic resistance genes[J]. Environmental Science & Technology, 2012, 46(21):11541-11549
[30]  Taviani E, Ceccarelli D, Lazaro N, et al. Environmental Vibrio spp. isolated in monitoring and evaluation mozambique, contain a polymorphic group of integrative conjugative elements and class 1 integrons[J]. FEMS Microbiol Ecol, 2008, 64:45-54
[31]  Li D, Yang M, Hu J Y, et al. Antibiotic-resistance profile in environmental bacteria isolated from penicillin production wastewater treatment plant and the receiving river[J]. Environmental Microbiology, 2009, 11(6):1506-1517
[32]  Guardabassi L, Wong D M A L F, Dalsgaard A. The effects of tertiary wastewater treatment on the prevalence of antimicrobial resistant bacteria[J]. Water Research,2002, 36:1955-1964
[33]  LaPara T M, Tucker R, Burzh P R, et al. Tertiary-treated municipal wastewater is a significant point source of antibiotic resistance genes into duluth-superior harbor[J]. Environmental Science & Technology, 2011, 45:9543-9549
[34]  Jacobs L, Chenia H Y. Characterization of integrons and tetracycline resistance determinants in Aeromonas spp. Isolated from South African aquaculture systems[J]. Int J Food Microbiol,2007: 114:295-306
[35]  Dang H Y, Zhang X X, Song L S, et al. Molecular characterizations of oxytetracycline resistant bacteria and their resistance genes from mariculture waters of China[J]. Mar Pollut Bull, 2006, 52:1494-1503
[36]  Dang H Y, Zhang X X, Song L S,et al. Molecular determination of oxytetracycline-resistant bacteria and their resistance genes from mariculture environments of China[J]. J Appl Microbiol, 2007, 103:2580-2592
[37]  Henriques I S, Moura A, Alves A, et al. Analysing diversity among β-lactamase encoding genes in aquatic environments[J]. FEMS Microbiol Ecol, 2006, 56:418-429
[38]  West B M, Liggit P, Clemans D L, et al. Antibiotic resistance, gene transfer, and water quality patterns observed in waterways near CAFO farms and wastewater treatment facilities[J]. Water Air Soil Pollut, 2010, 217:473-489
[39]  Caplin J L, Hanlon G W, Taylor H D. Presence of vancomycin and ampicillin-resistant Enterococcus faecium of epidemic clonal complex-17 in wastewaters from the south coast of England[J]. Environ Microbiol, 2008, 10:885-892
[40]  Zhang T, Zhang M, Zhang X X. Tetracycline resistance genes and tetracycline resistant lactose-fermenting enterobacteriaceae in activated sludge of sewage treatment plants[J]. Environmental Science & Technology, 2009, 43(10):3455-3460
[41]  Drewes J E, Heberer T, Reddersen K. Fate of pharmaceuticals during indirect potable reuse[J]. Water Science & Technology, 2002, 46:73-80
[42]  Carballa M, Omil F, Juan M. Behavior of pharmaceuticals, cosmetics and hormones in a sewage treatment plant[J]. Water Research, 2004, 36:2918-2926
[43]  Faria C, Vaz-Moreira I, Serapicos E, et al. Antibiotic resistance in coagulase negative staphylococci isolated from wastewater and drinking water[J]. Science of the Total Environment, 2009, 407:3876-3882
[44]  Da Silva M F, Vaz-Moreira I, Gonzalez-Pajuelo M, et al. Antimicrobial resistance patterns in Enterobacteriaceae isolated from an urban wastewater treatment plant[J]. FEMS Microbiol Ecol, 2007, 60:166-176
[45]  Castiglioni S, Pomati F, Miller K, et al. Novel homologs of the multiple resistance regulator marA in antibiotic-contaminated environments[J]. Water Research, 2008, 42:4281-4280
[46]  Koczura R, Mokracka J, Jabońska L, et al. Antimicrobial resistance of integron-harboring Escherichia coli isolates from clinical samples, wastewater treatment plant and river water[J]. Science of the Total Environment, 2012, 414:680-685
[47]  Zhang Y L, Marrs C F, Simon C. Wastewater treatment contributes to selective increase of antibiotic resistance among Acinetobacter spp.[J]. Science of the Total Environment, 2009, 407:3702-3706
[48]  Srinivasan V, Nam H M, Nguyen L T, et al. Prevalence of antimicrobial resistance genes in Listeria monocytogenes isolated from dairy farms[J]. Foodborne Pathog Dis, 2005, 2:201-211
[49]  Yang S, Carlson K. Evolution of antibiotic occurrence in a river through pristine, urban and agricultural landscapes[J]. Water Res, 2003, 37:4645-4656
[50]  Iversen A, Kühn I, Franklin A, et al. High prevalence of vancomycin-resistant enterococci in Swedish sewage[J]. Appl Environ Microbiol, 2002, 68:2838-2842
[51]  Szczepanowski R, Braun S, Riedel V, et al. The 120-592 bp IncF plasmid pRSB107 isolated from a sewage-treatment plant encodes nine different antibiotic-resistance determinants, two iron-acquisition systems and other putative virulence-associated functions[J]. Microbiology, 2005, 151:1095-1111
[52]  Mokracka J, Koczura R, Jabon'ska L. Phylogenetic groups, virulence genes and quinolone resistance of integron-bearing Escherichia coli strains isolated from a wastewater treatment plant[J]. Original Paper, 2011, 99:817-824
[53]  Heberer T, Stan H J. Determination of clofibric acid and N-(phenylsulfonyl)-sarcosine in sewage, river, and drinking water[J]. International Journal of Environmental Analytical Chemistry, 1997, 67:113-124
[54]  Rysz M, Alvarez P J J. Amplification and attenuation of tetracycline resistance in soil bacteria: Aquifer column experiments[J]. Water Research, 2004, 38:3705-3712
[55]  Pruden A, Pei R, Storteboom H, et al. Antibiotic resistance genes as emerging contaminants: Studies in Northern Colorado[J]. Environmental Science & Technology, 2006, 40(23):7445-7450
[56]  Liu Y F, Wang C H, Janapatla R P,et al. Presence of plasmid pA15 correlates with prevalence of constitutive MLSB resistance in group A streptococcal isolates at a university hospital in southern Taiwan[J]. J Antimicrob Chemother, 2007, 59:1167-1170
[57]  Agers? Y, Sandvang D. Class 1 integrons and tetracycline resistance genes in Alcaligenes, Arthrobacter, and Pseudomonas spp. isolated from pigsties and manured soil[J]. Applied Environment Microbiology, 2005, 71:7941-7947
[58]  Auerbach E A, Seyfried E E, McMahon K D. Tetracycline resistance genes in activated sludge wastewater treatment plants[J]. Water Research, 2007, 41(5):1143-1151
[59]  Munir M, Wong K, Xagoraraki I. Release of antibiotic resistant bacteria and genes in the effluent and biosolids of five wastewater utilities in Michigan[J]. Water Research, 2011, 45(2):681-693
[60]  ?uczkiewicz A, Jankowska K, Fudala-Ksiazek S, et al. Antimicrobial resistance of fecal indicators in municipal wastewater treatment plant[J]. Water research, 2010, 44:5089-5097
[61]  Volkmann H, Schwartz T, Bischoff P, et al. Detection of clinically relevant antibiotic-resistance genes in municipal wastewater using real-time PCR (TaqMan) [J]. J Microbiol Methods, 2004, 56:277-286
[62]  Ghosh S,Ramsden S J,Timothy M, et al. The role of anaerobic digestion in controlling the release of tetracycline resistance genes and class 1 integrons from municipal wastewater treatment plants[J]. Appl Microbiol Biotechnol, 2009, 84:791-796
[63]  Chen J, Frederick C, Michel J R, et al. Occurrence and persistence of erythromycin resistance genes (erm) and tetracycline resistance genes (tet) in waste treatment systems on swine farms[J]. Microb Ecol, 2010, 60:479-486
[64]  Martinez J L. Antibiotics and antibiotic resistance genes in natural environments[J]. Science, 2008, 321(5887):365-367
[65]  Knapp C W, Engemann C A, Hanson M L, et al. Indirect evidence of transposon-mediated selection of antibiotic resistance genes in aquatic systems at low-level oxytetracycline exposures[J]. Environmental Science & Technology, 2008, 42(14):5348-5353
[66]  Wu N, Qiao M, Zhang B, et al. Abundance and diversity of tetracycline resistance genes in soils adjacent to representative swine feedlots in China[J]. Environmental Science & Technology, 2010, 44(18): 6933-6939
[67]  Luo Y, Mao D Q, Rysz M, et al. Trends in antibiotic resistance genes occurrence in the Haihe River, China[J]. Environmental Science & Technology, 2010, 44(19):7220-7225
[68]  Li J, Shao B, Shen J Z, et al. Occurrence of chloramphenicol-resistance genes as environmental pollutants from swine feedlots[J]. Environmental Science & Technology, 2013,47(6):2892-2897
[69]  Rahube T O, Yost C K, et al. Antibiotic resistance plasmids in wastewater treatment plants and their possible dissemination into the environment[J]. African Journal of Biotechnology, 2010, 9(54):9183-9190
[70]  Schlüter A, Szczepanowski R, Pühler A, et al. Genomics of IncP-1 antibiotic resistance plasmids isolated from wastewater treatment plants provides evidence for a widely accessible drug resistance gene pool[J]. FEMS Microbiology Review., 2007, 31:449-477
[71]  Tennstedt T, Szczepanowski R, Braun S, et al. Occurrence of integron-associated resistance gene cassettes located on antibiotic resistance plasmids isolated from a wastewater treatment plant[J]. FEMS Microbiology Ecology, 2003, 45:239-252
[72]  Soda S, Otsuki H, Inoue D, et al. Transfer of antibiotic multiresistant plasmid RP4 from Escherichia coli to activated sludge bacteria[J]. Journal of Bioscience and Bioengineering, 2008, 106(3):292-296
[73]  Merlin C, Bonot S, Courtois S. Persistence and dissemination of the multiple-antibioticresistance plasmid pB10 in the microbial communities of wastewater sludge microcosms[J]. Water Reseasch, 2011, 45:2897-2905
[74]  王丽梅, 罗义, 毛大庆, 等. 抗生素抗性基因在环境中的传播扩散及抗性研究方法[J]. 应用生态学报, 2010, 21(4):1063-1069
[75]  马丽丽, 郭昌胜, 胡伟, 等. 固相萃取-高效液相色谱-串联质谱法同时测定土壤中氟喹诺酮、四环素和磺胺类抗生素[J]. 分析化学, 2010, 38(1):21-26
[76]  Pei R, Cha J, Carlson K H, et al. Response of antibiotic resistance genes (ARG) to biological treatment in dairy lagoon water [J]. Environmental Science & Technology, 2007, 41(14):5108-5113
[77]  Engemann C A, Keen P L, Knapp C W, et al. Fate of tetracycline resistance genes in aquatic systems: Migration from the water column to peripheral biofilms [J]. Environmental Science & Technology, 2008, 42(14):5131-5136
[78]  佟娟, 魏源送. 污水处理厂削减耐药菌与抗性基因的研究进展[J]. 环境科学学报, 2012, 32(11):2650-2659
[79]  Chen J, Yu Z T, Michel F C, et al. Development and application of real-time PCR assays for quantification of erm genes conferring resistance to macrolides-lincosamides-streptogramin B in livestock manure and manure management systems[J]. Appl Environ Microbiol, 2007, 73:4407-4416

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