Athanasiadou M, Cuadra SN, Marsh G, et al. Polybrominated diphenyl ethers (PBDEs) and bioaccumulative hydroxylated PBDE metabolites in young humans from Managua, Nicaragua[J].Environmental Health Perspectives, 2008, 116(2): 400-408
[2]
Zota AR, Park JS, Wang Y, et al. Polybrominated diphenyl ethers, hydroxylated polybrominated diphenyl ethers, and measures of thyroid function in second trimester pregnant women in California[J].Environmental Science Technology, 2011, 45(18):7896-7905
Olsen G W, Burris J M, Burlew M M, et al. Epidemiologic assessment of worker serum perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) concentrations and medical surveillance examinations[J].Journal of Occupational and Environmental Medicine, 2003, 45: 260-270
[5]
Dingemans M M, van den Berg M, Westerink R H. Neurotoxicity of brominated flame retardants: (in)direct effects of parent and hydroxylated polybrominated diphenyl ethers on the (developing) nervous system[J].Environmental Health Perspectives, 2011, 119(7): 900-907
[6]
McDonald T A. A perspective on the potential health risks of PBDEs[J].Chemosphere, 2002, 46(5): 745-755
Aagaard MM, Siersbaek R, Mandrup S. Molecular basis for gene-specific transactivation by nuclear receptors[J].Biochimica Et Biophysica Acta-Molecular Basis of Disease, 2011, 1812(8): 824-835
[11]
Ren X M, Guo L H. Molecular toxicology of polybrominated diphenyl ethers: Nuclear hormone receptor mediated pathways[J].Environmental Science-Processes & Impacts, 2013, 15(4): 702-708
[12]
Lau C, Anitole K, Hodes C, et al. Perfluoroalkyl acids: A review of monitoring and toxicological findings[J].Toxicological Sciences, 2007, 99(2): 366-394
[13]
Zhang J S, Lazar M A. The mechanism of action of thyroid hormones[J].Annual Review of Physiology, 2000, 62: 439-466
[14]
Hamers T, Kamstra J H, Sonneveld E, et al. Biotransformation of brominated flame retardants into potentially endocrine-disrupting metabolites, with special attention to 2,29,4,49-tetrabromodiphenyl ether (BDE-47)[J].Molecular Nutrition & Food Research, 2008, 52, 284-298
[15]
Marchesini G R, Meimaridou A, Haasnoot W, et al. Biosensor discovery of thyroxine transport disrupting chemicals[J].Toxicology and Applied Pharmacology, 2008, 232(1): 150-160
[16]
Kitamura S, Shinohara S, Iwase E, et al. Affinity for thyroid hormone and estrogen receptors of hydroxylated polybrominated diphenyl ethers[J].Journal of Health Science, 2008, 54(5): 607-614
[17]
Kojima H, Takeuchi S, Uramaru N, et al. Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells[J].Environmental Health Perspectives, 2009, 117(8): 1210-1218
[18]
Li F, Xie Q, Li X, et al. Hormone activity of hydroxylated polybrominated diphenyl ethers on human thyroid receptor-beta: In vitro and in silico investigations[J].Environmental Health Perspectives, 2010, 118(5): 602-606
[19]
Ibhazehiebo K, Iwasaki T, Kimura-Kuroda J, et al. Disruption of thyroid hormone receptor-mediated transcription and thyroid hormone-induced Purkinje cell dendrite arborization by polybrominated diphenyl ethers[J].Environmental Health Perspectives, 2011, 119(2): 168-175
[20]
Weiss J M, Andersson P L, Lamoree M H, et al. Competitive binding of poly- and perfluorinated compounds to the thyroid hormone transport protein transthyretin[J].Toxicological Sciences, 2009, 109(2): 206-216
[21]
Vongphachan V, Cassone C G, Wu D, et al. Effects of perfluoroalkyl compounds on mRNA expression levels of thyroid hormone-responsive genes in primary cultures of avian neuronal cells[J].Toxicological Sciences, 2011, 120(2): 392-402
[22]
Long M H, Ghisari M, Bonefeld-Jorgensen E C. Effects of perfluoroalkyl acids on the function of the thyroid hormone and the aryl hydrocarbon receptor[J].Environmental Science and Pollution Research, 2013, 20(11): 8045-8056
[23]
Cheng Y, Cui Y, Chen H M, et al. Thyroid disruption effects of environmental level perfluorooctane sulfonates (PFOS) in Xenopus laevis[J].Ecotoxicology, 2011, 20(8): 2069-2078
[24]
Cao J, Lin Y, Guo L H, et al. Structure-based investigation on the binding interaction of hydroxylated polybrominated diphenyl ethers with thyroxine transport proteins[J].Toxicology, 2010, 277(1/3): 20-28
[25]
Ren X M, Guo L H. Assessment of the binding of hydroxylated polybrominated diphenyl ethers to thyroid hormone transport proteins using a site-specific fluorescence probe[J].Environmental Science Technology, 2012, 46(8): 4633-4640
[26]
Ren X M, Guo L H, Gao Y, et al. Hydroxylated polybrominated diphenyl ethers exhibit different activities on thyroid hormone receptors depending on their degree of bromination[J].Toxicology and Applied Pharmacology, 2013, 268(3): 256-263
[27]
Ren X M, Zhang Y F, Guo L H, et al. Structure-activity relations in binding of perfluoroalkyl compounds to human thyroid hormone T3 receptor[J].Archives of Toxicology, 2014, DOI: 10.1007/s00204-014-1258-y
[28]
Heldring N, Pike A, Andersson S, et al. Estrogen receptors: How do they signal and what are their targets[J].Physiological Reviews, 2007, 87(3): 905-931
[29]
Meerts I A, Letcher R J, Hoving S, et al. In vitro estrogenicity of polybrominated diphenyl ethers, hydroxylated PBDEs, and polybrominated bisphenol A compounds[J].Environmental Health Perspectives, 2001, 109(4): 399-407
Hites RA. Polybrominated diphenyl ethers in the environment and in people: A meta-analysis of concentrations[J].Environmental Science Technology, 2004, 38(4): 945-956
[32]
Olsen G W, Burris J M, Ehresman D J, et al. Half-life of serum elimination of perfluorooctanesulfonate,perfluorohexanesulfonate, and perfluorooctanoate in retired fluorochemical production workers[J].Environmental Health Perspectives, 2007, 115: 1298-1305
[33]
Legler J. New insights into the endocrine disrupting effects of brominated flame retardants[J].Chemosphere, 2008, 73(2):216-222
[34]
Hamers T, Kamstra J H, Sonneveld E, et al. In vitro profiling of the endocrine-disrupting potency of brominated flame retardants[J].Toxicological Sciences, 2006, 92(1): 157-173
[35]
Yang W H, Wang Z Y, Liu H L, et al. Exploring the binding features of polybrominated diphenyl ethers as estrogen receptor antagonists: Docking studies[J].Sar and Qsar in Environmental Research, 2010, 21(3/4): 351-367
[36]
Benninghoff A D, Bisson W H, Koch D C, et al., Estrogen-like activity of perfluoroalkyl acids in vivo and interaction with human and rainbow trout estrogen receptors in vitro[J].Toxicological Sciences, 2011, 120(1): 42-58
[37]
Li X, Gao Y, Guo LH, et al., Structure-dependent activities of hydroxylated polybrominated diphenyl ethers on human estrogen receptor[J].Toxicology, 2013, 309: 15-22
[38]
Gao Y, Li X, Guo LH. Assessment of estrogenic activity of perfluoroalkyl acids based on ligand-induced conformation state of human estrogen receptor[J].Environmental Science Technology, 2013, 47(1): 634-641
[39]
Bloom M S, Kannan K, Spliethoff H M, et al. Exploratory assessment of perfluorinated compounds and human thyroid function[J].Physiology & Behavior, 2010, 99(2): 240-245
[40]
Luebker D J, Hansen K J, Bass N M, et al. Interactions of flurochemicals with rat liver fatty acidbinding protein[J].Toxicology, 2002, 176: 175-185
[41]
Zhang L, Ren XM, Guo LH. Structure-based investigation on the interaction of perfluorinated compounds with human liver fatty acid binding protein[J].Environmental science technology, 2013, 47 (19): 11293-11301
[42]
Zhang L, Ren X M, Wan B, et al. Structuredependent binding and activation of perfluorinated compounds on human peroxisome proliferator-activated receptor γ[J].Toxicology and Applied Pharmacology, 2014,279(3):275-283
