|
OALib Journal期刊
ISSN: 2333-9721
费用：99美元
|
|
|
|
NIR触发的两亲性含糖聚合物修饰的纳米金棒的制备及应用
DOI: 10.11777/j.issn1000-3304.2015.15157, PP. 1128-1132
Keywords: 含糖聚合物,纳米金棒,可控释放
Abstract:
通过配体交换的方法成功将含糖聚合物PGAMA14-PCL32-SH接枝到纳米金棒的表面(Gly@AuNRs).借助X-射线光电子能谱(XPS)、动态光散射(DLS)、热重分析(TGA)等对Gly@AuNRs进行了表征.为了得到药物控释所需要的合适的实验条件,研究了近红外光照射下Gly@AuNRs在水溶液中的光热转换行为.用Gly@AuNRs包裹药物姜黄素(CUR),研究了药物的体外释放,发现近红外光能有效控制药物的体外释放.细胞实验结果表明含糖聚合物的接枝大大提高了纳米金棒的生物相容性.因此,Gly@AuNRs复合材料能够作为生物相容性载体材料,并实现近红外光触发的药物的可控释放.
| [1] | 13 Kiessling L L,Grim J C.Chem Soc Rev,2013,42:4476~4491
|
| [2] | 14 Ladmiral V,Melia E,Haddleton D M.Eur Polym J,2004,40:431~449
|
| [3] | 15 Lipinski T,Kitov P I,Szpacenko A,Paszkiewicz E,Bundle D R.Bioconjugate Chem,2011,22:274~281
|
| [4] | 16 Ponader D,Wojcik F,Beceren-Braun F,Dernedde J,Hartmann L.Biomacromolecules,2012,13:1845~1852
|
| [5] | 17 Shi Q Meng J Q,Xu R S,Du X L,Zhang Y F.J Membr Sci,2013,444:50~59
|
| [6] | 18 Vetere A,Donati I,Campa C,Semeraro S,Gamini A,Paoletti S.Glycobiology,2002,12:283~290
|
| [7] | 19 Pei D F,Li Y C,Huang Q R,Ren Q,Li F,Shi T F.Coll Surf B-Biointerfaces,2015,126:367~373
|
| [8] | 20 Gou L F,Murphy C J.Chem Mater,2005,17:3668~3672
|
| [9] | 1 Yang D P, Cui D X.Chemistry-an Asian Journal,2008,3:2010~2022
|
| [10] | 2 Alkilany A M,Thompson L B,Boulos S P,Sisco P N,Murphy C J.Adv Drug Deliv Rev,2012,64:190~199
|
| [11] | 3 Huang X H,Neretina S,El-Sayed M A.Adv Mater,2009,21:4880~4910
|
| [12] | 4 Manohar S,Ungureanu C,Van Leeuwen T G.Contrast Media Mol Imag,2011,6:389~400
|
| [13] | 5 Mirza A Z.J Drug Target,2015,23:52~58
|
| [14] | 6 Wijaya A,Schaffer S B,Pallares I G,Hamad-Schifferli K.ACS Nano,2009,3:80~86
|
| [15] | 7 Liu J,Detrembleur C,Grignard B,De Pauw-Gillet M C,Mornet S.Chemistry-an Asian Journal,2014,9:275~288
|
| [16] | 8 Niidome T.Yakugaku Zasshi-Journal of the Pharmaceutical Society of Japan,2013,133:369~372
|
| [17] | 9 Zhong Y N,Wang C,Cheng L,Meng F H,Zhong Z Y,Liu Z.Biomacromolecules,2013,14:2411~2419
|
| [18] | 10 Nikoobakht B,El-Sayed M A.Chem Mater,2003,15:1957~1962
|
| [19] | 11 Conversano F,Soloperto G,Casciaro E,Greco A,Casciaro S,Ragusa A.Intern Ultrasonics Symp(Ius),2012,8:2321~2324
|
| [20] | 12 Grabinski C,Schaeublin N,Wijaya A,D'Couto H,Baxamusa S H,Hamad-Schifferli K,Hussain S M.ACS Nano,2011,5:2870~2879
|
Full-Text
|
|
Contact Us
service@oalib.com QQ:3279437679 
WhatsApp +8615387084133
|
|
