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OALib Journal期刊
ISSN: 2333-9721
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具有X-射线自显影功能的碘代聚氨酯栓塞剂材料的研究
DOI: 10.3724/SP.J.1105.2014.13145, PP. 31-39
Keywords: 聚氨酯,碘代双酚A,X-射线自显影,栓塞剂
Abstract:
设计合成四碘代双酚A（IBPA）作为扩链剂，以聚丁二酸丁二醇酯（PBS-OH）为软段、异佛尔酮二异氰酸酯（IPDI）和IBPA为硬段，通过偶联反应获得一种新型X-射线聚氨酯显影材料.红外光谱和核磁共振氢谱确定所合成碘代聚氨酯（I-PUs）的结构与组成，并用示差扫描量热法，热重分析，X-射线衍射仪和临床X-射线仪评价不同IBPA含量的碘代聚氨酯的热性能、结晶性和显影效果.结果表明，碘代扩链剂IBPA较高含量的引入对聚合物的热稳定性有一定的影响，并促使聚氨酯由结晶态向非晶态转变.引入IBPA对聚氨酯的显影效果有很好的促进增强作用，聚氨酯材料及微球均具有较好的X光显影效果.噻唑蓝比色法（MTT）评价细胞毒性证实制备的较高碘含量的聚氨酯材料均无细胞毒性，是一种很好的血管栓塞剂材料.
| [1] | 10 Cabasso I, Smid J, Sahni S K.J Appl Polym Sci, 1989, 38:1653~1666
|
| [2] | 11 Wang X, Geng X, Ye L, Zhang A Y, Feng Z G.React Funct Polym, 2009, 69:857~863
|
| [3] | 12 Mawad D, Mouaziz H, Penciu A, Mehier H, Fenet B, Fessi H, Chevalier Y.Biomaterials, 2009, 30:5667~5674
|
| [4] | 13 Habnouni S E, Darcos V, Coudane J.Macromol Rapid Commun, 2009, 30:165~169
|
| [5] | 14 Aviv H, Bartling S, Kieslling F, Margel S.Biomaterials, 2009, 30:5610~5616
|
| [6] | 15 James N R, Jayakrishnan A.Biomaterials, 2007, 28:3182~3187
|
| [7] | 16 James N R, Philip J, Jayakrishnan A.Biomaterials, 2006, 27:160~166
|
| [8] | 21 Zhang Zhihua(张智华), Qu Weiqiang(曲伟强), Tuo Xinlin(庹新林).Acta Polymerica Sinica(高分子学报), 2012, (5):546~551
|
| [9] | 22 Edgar K J, Falling S N.J Org Chem, 1990, 55:5287~5291
|
| [10] | 23 Barros M T, Dey S S, Maycock C D, Rodrigues P.Chem Commum, 2012, 48:10901~10903
|
| [11] | 27 Stacul F.Eur Radiol, 2001, 11:690~697
|
| [12] | 28 Saralidze K, van Hooy-Corstjens C S, Koole L H, Knetsach M L.Biomaterials, 2008, 28:2457~2464
|
| [13] | 29 van Hooy-Corstjens C S, Saralidze K, Knetsch M L, Emans P J, Magusin P M, Mezari B, Koole L H.Biomacromolecules, 2008, 9:84~90
|
| [14] | 1 Chapple C R, Wein A J, Brubaker L, Dmochowski R, Pons M E, Haab F.Eur Urol, 2005, 48:552~565
|
| [15] | 2 Matsumaru Y, Hyodo A, Nose T, Hirano T, Ohashi S.J Biomat Sci:Polym Ed, 1997, 8:555~569
|
| [16] | 3 Qureshi A I.The Lancet, 2004, 363:804~813
|
| [17] | 4 Lookstein R A, Guller J.The Mount Sinai J Med, 2004, 71:17~28
|
| [18] | 5 Menei P, Venier E, Gamelin E, Saint-Andre J P, Hayek G, Jadaud E, Fournier D, Mercier P, Guy G, Benoit J P.Cancer, 1999:325~330
|
| [19] | 6 Benoit J P, Faisant N, Venier-Julienne M C, Menei P.J Control Release, 2000:285~296
|
| [20] | 7 Fournier E, Passirani C, Colin N, Breton P, Sagodira S, Benoit JP.Eur J Pharm Biopharm, 2004, 57:189~197
|
| [21] | 8 Thanoo BC, Sunny M C, Jayakrishnan A.Biomaterials, 1991, 12:525~528
|
| [22] | 9 Jayakrishnan A, Thanoo B C.J Appl Polym Sci, 1992, 44:743~748
|
| [23] | 17 Kiran S, James N R, Joseph R, Jayakrishnan A.Biomaterials, 2009, 30:5552~5559
|
| [24] | 18 Kiran S, James N R, Jayakrishnan A, Joseph R.J Biomed Mater Res Part A, 2012, 100:3472~3479
|
| [25] | 19 Xia Weijuan(夏维娟), Tuo Xinlin(庹新林), Lian Yanqing(连彦青), Wang Xiaogong(王晓工).Acta Polymerica Sinica(高分子学报), 2009, (4):369~374
|
| [26] | 20 Qu W Q, Xia W J, Feng C, Tuo X L, Qiu T.J Polym Sci Part A:Polym Chem, 2011, 49:2191~2198
|
| [27] | 24 Wei Z J, Wang C Y, Zou S W, Liu H, Tong Z.Polymer, 2012, 53:1229~1235
|
| [28] | 25 Chen H, Wang X, Zeng J, Li L, Dong F, Wang Y.Ind Eng Chem Res.2011, 50:2065~2072
|
| [29] | 26 Sovak M.Eur Radiol, 1995, 5:3~7
|
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