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OALib Journal期刊
ISSN: 2333-9721
费用：99美元
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几种抗生素与人血清白蛋白结合反应的研究
, PP. 2169-2173
Keywords: 人血清白蛋白,头孢噻肟钠,苯唑西林,阿莫西林,诺氟沙星,依诺沙星,荧光光谱法
Abstract:
用荧光法研究了头孢噻肟钠、苯唑西林、阿莫西林、诺氟沙星、依诺沙星等五种抗生素类药物与人血清白蛋白的结合反应,测得26℃时的结合常数KA分别为1.98×104,1.01×103,1.38×103,5.97×104和7.15×104L·mol-1,结合位点数n分别为1.16,0.86,1.19,0.91和0.93.确定了这些药物与人血清白蛋白之间的主要结合力为静电作用力.
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