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化学学报  2012 

取代薁酮的反应性研究:秋水仙碱合成新策略的探索

DOI: 10.6023/A12070432, PP. 2029-2036

Keywords: 薁酮,互变异构,重排,秋水仙碱,全合成

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Abstract:

本工作以探索秋水仙碱(Colchicine)合成新策略为目标,研究了烷氧基取代薁酮2a的独特反应性,发现了一系列罕见的重排过程和环庚三烯(Tropilidene)降蒈二烯(Norcaradiene)互变异构现象,探讨了相应的反应机理.

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