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大肠杆菌启动子特征元件对启动子识别的影响

Keywords: 神经网络,大肠杆菌,启动子

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Abstract:

为了进一步研究大肠杆菌启动子的识别算法,根据大肠杆菌基因分子生物学有关理论与统计事实,对大肠杆菌启动子特征元件进行了研究.从启动子样本中选取不同的保守序列,采用2种神经网络结构.分别分析了启动子特征元件对识别的影响.研究发现.包含-10和-35区2个显著保守序列元件及其他几个非显著序列元件时,正样本和负样本的识别率最高,达到77.67%和88.45%.实验结果为进一步研究启动子的特征提取和识别算法提供了参考.

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