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化学进展 1999

化学多样性空间探索与组合药物设计

徐峻

Keywords: 组合化学,药物设计,高速筛选技术,化学多样性,微珠编码,多组分缩合反应,虚拟组合化学库

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Abstract:

本文综述组合化学的最新进展,内容涵盖组合化学的基本概念、原理、技术,在药物发现中的应用,以及组合化学和其他科学技术分枝的关系。最后,提出了组合化学工程中亟须研究的一些项目,介绍了开展这些研究所必需的条件,并给出了解决方案。

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