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化学进展  2012 

电化学发光分析方法在核酸检测中的应用

, PP. 2367-2373

Keywords: 电化学发光,核酸检测,核酸钌标记

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Abstract:

电化学发光(electrochemiluminescence,ECL)分析方法具有灵敏、快速、准确、分析适应性广等特点。本文首先介绍了ECL的基本原理和特点、ECL核酸分析方法的分类和核酸的钌标记,随后对2003年以来基于磁性微球的ECL与核酸扩增及纳米技术联用在核酸检测中的应用、直接固定的ECL核酸分析方法及毛细管电泳(CE)-ECL核酸分析方法的应用做出了评述,并对ECL核酸分析方法的发展方向进行了展望。

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