Sussman J L, Harel M, Frolow F, Oefner C, Goldman A, Toker L, Silman I. Science, 1991, 253: 872—879
[2]
Johnson G, Moore S W. Curr. Pharm. Des., 2006, 12: 217—225
[3]
Inestrosa N C, Dinamarca M C, Alvarez A. FEBS J., 2008, 275: 625—632
[4]
Correa-Basurto J, Flores-Sandoval C, Marín-Cruz J, Rojo-Domínguez A, Espinoza-Fonseca L M, Trujillo-Ferrara J G. Eur. J. Med. Chem., 2007, 42: 10—19
[5]
Xie Q, Wang H, Xia Z, Lu M, Zhang W, Wang X, Fu W, Tang Y, Sheng W, Li W, Zhou W, Zhu X, Qiu Z, Chen H. J. Med. Chem., 2008, 51: 2027—2036
[6]
Alonso D, Dorronsoro I, Rubio L, Muňoz P, García-Palomero E, Monte M D, Bidon-Chanal A, Orozco M, Luque F J, Castro A, Medina M, Martínez A. Bioorg. Med. Chem., 2005, 13: 6588—6597
[7]
Camps P, Formosa X, Mun？z-Torrero D, Petrignet J, Badia A, Clos M V. J. Med. Chem., 2005, 48: 1701—1704
[8]
Bolognesi M L, Andrisano V, Bartolini M, Banzi R, Melchiorre C. J. Med. Chem., 2005, 48: 24—27
[9]
Belluti F, Piazzi L, Bisi A, Gobbi S, Bartolini M, Cavalli A, Valenti P, Rampa A. Eur. J. Med. Chem., 2009, 44: 1341—1348
[10]
Mohamed T, Yeung J C K, Rao P P N. Bioorg. Med. Chem. Lett., 2011, 21: 5881—5887
[11]
Tang H, Zhao L Z, Zhao H T, Huang S L, Zhong S M, Qin J K, Chen Z F, Huang Z S, Liang H. Eur. J. Med. Chem., 2011, 46: 4970—4979
[12]
Tang H, Zhao H T, Zhong S M, Wang Z Y, Chen Z F, Liang H. Bioorg. Med. Chem. Lett., 2012, 22: 2257—2261
[13]
Bareggi S R, Cornelli U. CNS Neurosci. Ther., 2012, 18: 41—46
[14]
León R, Garcia A G, Marco-Contelles J. Med. Res. Rev., 2013, 33: 139—189
[15]
Rosini M, Andrisano V, Bartolin M, Bolognesi M L, Hrelia P, Minarini A, Tarozzi A, Melchiorre C. J. Med. Chem., 2005, 48: 360—363
[16]
Cavalli A, Bolognesi M L, Capsoni S, Andrisano V, Bartolini M, Margotti E, Cattaneo A, Recanatini M, Melchiorre C. Angew. Chem. Int. Ed., 2007, 46: 3689—3692
[17]
Bolognesi M L, Cavalli A, Valgimigli L, Bartolini M, Rosini M, Andrisano V, Recanatini M, Melchiorre C. J. Med. Chem., 2007, 50: 6446—6449
[18]
Rodríguez-Franco M I, Fernández-Bachiller M I, Pérez C, Hernández-Ledesma B, Bartolomé B. J. Med. Chem., 2006, 49: 459—462
[19]
Alipour M, Khoobi M, Foroumadi A, Nadri H, Moradi A, Sakhteman A, Ghandi M, Shafiee A. Bioorg. Med. Chem., 2012, 20: 7214—7222
[20]
Viayna E, Gómez T, Galdeano C, Ramírez L, Ratia M, Badia A, Clos M V, Verdaguer E, Junyent F, Camins A, Pallàs M, Bartolini M, Mancini F, Andrisano V, Arce M P, Rodríguez-Franco M I, Bidon-Chanal A, Luque F J, Camps P, Mu？oz-Torrero D. ChemMedChem 2010, 5: 1855—1870
[21]
Belluti F, Bartolini M, Bottegoni G, Bisi A, Cavalli A, Andrisano V, Rampa A. Eur. J. Med. Chem., 2011, 46: 1682—1693
[22]
Mun？z-Ruiz P, Rubio L, García-Palomero E, Dorronsoro I, del Monte-Millán M, Valenzuela R, Usán P, de Austria C, Bartolini M, Andrisano V, Bidon-Chanal A, Orozco M, Luque F J, Medina M, Martínez A. J. Med. Chem., 2005, 48: 7223—7233
[23]
Belluti F, Rampa A, Piazzi L, Bisi A, Gobbi S, Bartolini M, Andrisano V, Cavalli A, Recanatini M, Valenti P. J. Med. Chem., 2005, 48: 4444—4456
[24]
Piazzi L, Belluti F, Bisi A, Gobbi S, Rizzo S, Bartolini M, Andrisano V, Recanatini M, Rampa A. Bioorg. Med. Chem., 2007, 15: 575—585
[25]
Luo W, Li Y P, He Y, Huang S L, Tan J H, Ou T M, Li D, Gu L Q, Huang Z S. Bioorg. Med. Chem., 2011, 19: 763—770
[26]
Fernández-Bachiller M I, Pérez C, Campillo N E, Páez J A, González-Mun？oz G C, Usán P, García-Palomero E, López M G, Villarroya M, García A G, Martínez A, Rodríguez-Franco M I. ChemMedChem, 2009, 4: 828—841
[27]
Fernández-Bachiller M I, Pérez C, González-Mu？oz G C, Conde S, López M G, Villarroya M, García A G, Rodríguez-Franco M I. J. Med. Chem., 2010, 53: 4927—4937
[28]
Fernaández-Bachiller M I, Pérez C, Monjas L, Rademann J, Rodríguez-Franco M I. J. Med. Chem., 2012, 55: 1303—1317
[29]
Pisani L, Catto M, Giangreco I, Leonetti F, Nicolotti O, Stefanachi A, Cellamare S, Carotti A. ChemMedChem, 2010, 5: 1616—1630
[30]
Catto M, Pisani L, Leonetti F, Nicolotti O, Pesce P, Stefanachi A, Cellamare S, Carotti A. Bioorg. Med. Chem., 2013, 21: 146—152
[31]
Zheng W, Li J, Qiu Z, Xia Z, Li W, Yu L, Chen H, Chen J, Chen Y, Hu Z, Zhou W, Shao B, Cui Y, Xie Q, Chen H. Toxicol. Appl. Pharmacol., 2012, 264: 65—72
[32]
Wimo A, Prince M. World Alzheimer Report 2010. Alzheimer's Disease International. (2010-09-21).[2011-06]. http://www. alz. co. uk/research/files/WorldAlzheimerReport2010. pdf
[33]
Tayeb H O, Yang H D, Price B H, Taraz F I. Pharmacol. Therapeut., 2012, 134: 8—25
[34]
Karran E, Mercken M, Strooper B D. Nat. Rev. Drug Discov., 2011, 10: 698—712
[35]
Huang Y, Mucke L. Cell, 2012, 148: 1204—1222
[36]
Pang Y P, Quiram P, Jelacic T, Hong F, Brimijoin S. J. Biol. Chem., 1996, 271: 23646—23649
[37]
Carlier P R, Han Y F, Chow E S H, Li C P L, Wang H, Lieu T X, Wong H S, Pang Y P. Bioorg. Med. Chem., 1999, 7: 351—357
[38]
Muoz-Torrero D, Camps P. Curr. Med. Chem., 2006, 13: 399—422
[39]
Nie H, Yu W J, Li X Y, Yuan C H, Pang Y P, Li C Y, Han Y F, Li Z W. Neurosci. Lett., 2007, 412: 108—113
[40]
Guillou C, Mary A, Renko D Z, Gras E, Thal C. Bioorg. Med. Chem. Lett., 2000, 10: 637—639
[41]
Decker M. J. Med. Chem., 2006, 49: 5411—5413
[42]
He X C, Feng S, Wang Z F, Shi Y, Zheng S, Xia Y, Jiang H, Tang X, Bai D. Bioorg. Med. Chem., 2007, 15: 1394—1408
[43]
Wang R, Yan H, Tang X. Acta Pharmacol. Sin., 2006, 27: 1—26
[44]
Haviv H, Wong D M, Greenblatt H M, Carlier P R, Pang Y P, Silman I, Sussman J L. J. Am. Chem. Soc., 2005, 127: 11029—11036
[45]
Paz A, Xie Q, Greenblatt H M, Fu W, Tang Y, Silman I, Qiu Z, Sussman J L. J. Med. Chem., 2009, 52: 2543—2549
[46]
Tumiatti V, Milelli A, Minarini A, Rosini M, Bolognesi M L, Micco M, Andrisano V, Bartolini M, Mancini F, Recanatini M, Cavalli A, Melchiorre C. J. Med. Chem., 2008, 51: 7308—7312
[47]
Gemma S, Gabellieri E, Huleatt P, Fattorusso C, Borriello M, Catalanotti B, Butini S, Angelis M D, Novellino E, Nacci V, Belinskaya T, Saxena A, Campiani G. J. Med. Chem., 2006, 49: 3421—3425
