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OALib Journal期刊
ISSN: 2333-9721
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生物法与化学法制备硫酸软骨素
DOI: 10.7536/PC140312, PP. 1378-1394
Keywords: 硫酸软骨素,化学合成,生物催化,硫酸化代码
Abstract:
硫酸软骨素（ChS）是一种天然的酸性黏多糖，生物活性多样，在医学、生物、制药、食品、化妆品和材料等领域均有广泛应用，特别是在治愈骨关节病上具有颇为理想的效果。本文系统地总结了有关硫酸软骨素及其类似物的生物与化学制备方法的研究进展，如高产微生物菌株筛选与改良，培养条件优化与调控，汇聚式合成策略构建，经济易得的起始物原料等，并指出制备硫酸软骨素中存在的问题以及发展方向。
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