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OALib Journal期刊
ISSN: 2333-9721
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苯丙氨酸二肽类分子自组装：分子设计、结构调控与材料应用
DOI: 10.7536/PC140503, PP. 1445-1459
Keywords: 苯丙氨酸二肽,超分子自组装,共组装,酶催化组装,传感,药物传递,组织工程
Abstract:
近年来，苯丙氨酸二肽类分子的自组装研究受到了广泛关注，已成为超分子化学、生物材料科学研究的前沿领域之一。苯丙氨酸二肽类纳米组装体因具有结构多样、易功能化以及良好的生物相容性等优点，在纳米制造、组织修复等方面展示出巨大的应用潜力。本文从分子设计、组装结构调控与材料应用三个层次系统综述了苯丙氨酸二肽类分子自组装的研究进展。首先总结了苯丙氨酸二肽类分子的修饰改性，包括乙酰基、芳香环、氨基酸、短肽等基团。然后，重点介绍了苯丙氨酸二肽类分子自组装的调控策略和方法，如溶剂、界面、气相、多组分共组装和酶催化组装。最后，介绍了苯丙氨酸二肽类自组装材料在纳米材料合成、传感检测、药物传递及组织修复等方面的应用现状，并分析了该领域今后的发展方向。
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