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化学进展 2014

基于SERS技术的核酸检测

DOI: 10.7536/PC140355, PP. 1516-1526

宋春元,杨琰君,汪联辉

Keywords: 表面增强拉曼散射(SERS),核酸检测,SERS探针

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Abstract:

表面增强拉曼散射（SERS）技术因其具有超灵敏和非破坏性的检测能力，在生命科学领域已经显示出巨大的应用潜力和研究价值。本文综述了SERS技术在核酸检测方面的最新研究进展，重点介绍了基于SERS技术的非标记型、标记型以及其他一些检测方法的原理及研究成果，并讨论了基于SERS的核酸检测技术有待进一步解决的关键问题。

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