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OALib Journal期刊
ISSN: 2333-9721
费用：99美元
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正碳离子样的过渡态类似物研究进展*
, PP. 1048-1053
Keywords: 酶,正碳离子,过渡态类似物,抑制剂
Abstract:
综述了应用酶催化过渡态理论设计的几类正碳离子样的过渡态类似物作为酶的抑制剂的研究进展。其中包括类异戊二烯的正离子过渡态类似物,唾液酸转移酶的过渡态类似物,3-脱氧-D-甘露糖-2-辛酮糖酸酯-8-磷酸酯(KDO8P)合成酶的过渡态类似物,尿苷二磷酸酯葡糖醛酸基转移酶(UGT)的过渡态类似物。
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