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OALib Journal期刊
ISSN: 2333-9721
费用：99美元
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蝴蝶霉素及其类似物的化学合成进展
, PP. 1699-1707
Keywords: 蝴蝶霉素,抗生素,先导化合物,化学合成
Abstract:
蝴蝶霉素是一种新型的天然抗生素，由于具有特殊的抗肿瘤活性而引起了人们的关注。然而，由于一些不利因素导致蝴蝶霉素无法直接运用于临床。为了寻找活性更好的药物先导化合物，人们对蝴蝶霉素的结构进行修饰和改造，通过生物方法和化学方法，合成了大量的类似物。本文将从化学合成角度出发，立足蝴蝶霉素及其类似物结构构造的关键步骤，对近年来的合成研究进行综述。
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