OALib Journal期刊
金属卟啉核酸定位断裂剂的设计及氧化断裂研究
Keywords: 金属卟啉 ,核酸 ,定位识别 ,氧化断裂
Abstract:
金属卟啉连接到一些特殊基团如寡聚核苷酸、蛋白肽链、吖啶等上时,可达到对DNA的定位断裂,这在核酸探针及抗癌剂的设计中具有重要的作用。本文就近年来国内外在金属卟啉对DNA的定位识别及在PhIO、KHSO5、O2?还原剂等存在下,对DNA定位氧化断裂等方面的研究进展进行了综述,可供该方向的研究人员参考。
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