全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用：99美元
投递稿件

查看量下载量

相关文章

更多...
化学进展  2002 

金属在生物和医学中的作用

Keywords: 无机药物,疾病,金属

Full-Text   Cite this paper   Add to My Lib

Abstract:

金属元素在整个生命体系中起着重要的作用。金属离子与核酸、蛋白质等生物大分子的作用以及对神经系统的不正常的影响可以直接或间接地损伤DNA从而引起细胞的变异，进而导致各种疾病；同时我们可以根据这些特性研究金属离子的药物用于各种疾病的诊断和治疗。本文着重介绍了几种重要的金属和无机药物。

 References

[1]  [ 3 ] J. Inorg. Biochem. , 2000, 82: 1—249
[2]  [ 4 ] Atwood C S, Huang X, Moir R D, Tanzi R E, Bush A L.Met. Ions Biol. Syst. , 1999, 36: 309—364
[3]  [ 5 ] Kong J , Xu Z J. Neuroscience, 1998, 18: 3241—3250
[4]  [ 6 ] Pasinelli P, Borchelt D R, Houseweart M K, et al. Proc.Natl. Acad. Sci. USA , 1998, 95: 15763—15768
[5]  [ 7 ] Bush A. Curr. Opin. Chem. Biol. , 2000, 4: 184—191
[6]  [ 8 ] Symons M C R, Gutteridge J M C. Free Radicals and Iron: Chemistry, Biology, and Medicine. Oxford: Oxford Science Publications, 1998
[7]  [ 11 ] Gunsh in H, Mackenzie B, Berger U V , et al. Nature,1997, 388: 482—488
[8]  [ 14 ] Mercer J F. Trends Mol. Med. , 2001, 7: 64—69
[9]  [ 15 ] Sarkar B. Chem. Rev. , 1999, 99 (9) : 2535—2544
[10]  [ 16 ] Bull P C, Thomas G R, Rommens J M , et al. Nat.Genet. , 1993, 5: 327—337
[11]  [ 20 ] Samaia H R, Mari J J , Vallada H P, Moura R P, et al.Nature, 1997, 390: 241
[12]  [ 22 ] Lehamann S. Curr. Opin. Chem. Biol. , 2002, 6: 187—192
[13]  [ 23 ] Andrews N C. Curr. Opin. Chem. Biol. , 2002, 6: 181—186
[14]  [ 24 ] Metal-Based Anti-Tumour Drugs ( ed. Gielen M ). London: Freund Publishing House Ltd. , 1998
[15]  [ 25 ] Metal Complexes in Cancer Chemotherapy (ed. Keppler B K). Weinheim:VCH, 1993
[16]  [ 26 ] Sadler P J , Guo Z. Pure Appl. Chem. , 1998, 70: 863—871
[17]  [ 29 ] Guo Z, Sadler P J. Adv. Inorg. Chem. , 2000, 49: 183—306
[18]  [ 30 ] Rosenberg B, Van C L , Krigas T. Nature, 1965, 205:698—699
[19]  [ 33 ] Clarke M J , Zhu F, Frasca D R. Chem. Rev. , 1999, 99(9) : 2511—2533
[20]  [ 40 ] Zhang Y, Bendahan A , Zarbiv R, et al. Proc. Natl. Acad. Sci. USA , 1998, 95: 751—755
[21]  [ 42 ] Moyer C A , Brentano L , Gravens D L , et al. Arch.Surg. , 1965, 90: 812—867
[22]  [ 44 ] Fox C L. J. Trauma, 1969, 9: 387—388
[23]  [ 45 ] Fox C L , Modak S A. Antimicrob. Agents Chemother. ,1974, 5: 582—588
[24]  [ 47 ] Shen Z X, Chen G Q , Ni J H, et al. Blood, 1997, 89:3354—3360
[25]  [ 49 ] Chou W C, Hawkins A L , Barrett J F, et al. J. Clin. Invest. , 2001, 108: 1541—1547
[26]  [ 50 ] Shaw C F III. Comments Inorg. Chem. , 1989, 8: 233—239
[27]  [ 54 ] Parish R V , Howe B P, Wright J P, et al. Inorg. Chem. ,1996, 35: 1659—1666
[28]  [ 55 ] Tepperman K, Shinju Y, Roy P, et al. Metal-Based Drugs, 1994, 1: 433—444
[29]  [ 56 ] Navarro M , Pérez H, Sánchez-Delgado R A. J. Med.Chem. , 1997, 40: 1937—1939
[30]  [ 57 ] Slikkerveer A F, Wolff A. Med. Toxicol. Adverse Drug Exp. , 1989, 4: 303—323
[31]  [ 59 ] Sun H, Li H, Sadler P J. Chem. Ber./Recueil, 1997,130: 669—681
[32]  [ 60 ] Sadler P J , Li H, Sun H. Coord. Chem. Rev. , 1999,185: 689—709
[33]  [ 61 ] Briand G G, Barford N. Chem. Rev. , 1999, 99: 2601—2602
[34]  [ 62 ] Sun H, Sadler P J. Top. Biol. Inorg. Chem. , 1999, 2:159—186
[35]  [ 63 ] Blaser M. Gastroenterology, 1992, 102: 720—727
[36]  [ 64 ] Tomb J F, White O , Kerlavage A R, et al. Nature, 1997,388: 539—547
[37]  [ 65 ] Li H, Sadler P J , Sun H. J. Biol. Chem. , 1996, 271:9483—9489
[38]  [ 70 ] Sharp P F, Smith F W , Gemmell H G, et al. J. Nucl.M ed. , 1986, 27: 171—177
[39]  [ 1 ] Wilkins P C, Wilkins R G. Inorganic Chemistry in Biology. Oxford: Oxford University Press, 1997
[40]  [ 2 ] Abrams M J , Murrer B A. Science, 1993, 261: 725—730
[41]  [ 9 ] Hanson E H, Imperatore G, Burck W. Am. J. Epidemiol. , 2001, 154: 193—206
[42]  [ 10 ] Feder J N , Gnirke A , Thomas W , et al. Nat. Genet. ,1996, 13: 399—408
[43]  [ 12 ] Donovan A , Brownlie A , Zhou Y, et al. Nature, 2000,403: 776—781
[44]  [ 13 ] Andrews N C. Nat. Rev. Genet. , 2000, 1: 208—217
[45]  [ 17 ] Tanzi R E, Petrukhin K, Chernov I, et al. Nat. Genet. ,1993, 5: 344—350
[46]  [ 18 ] Miura T, Hori-iA , Takeuchi H. FEBS Lett. , 1996, 396:248—252
[47]  [ 19 ] Prusiner S B. Science, 1997, 278: 245—251
[48]  [ 21 ] Brown D R, Qin K, Herms J W , Madlung A , et al. Nature, 1997, 390: 684—687
[49]  [ 27 ] Guo Z, Sadler P J. Angew. Chem. Int. Ed. , 1999, 38:1512—1531
[50]  [ 28 ] Metal Compounds in Cancer Therapy (ed. Fricher S P ).London: Chapman & Hall, 1994
[51]  [ 31 ] Zamble D B, Lippard S J. Trends Biochem. Sci. , 1995,20: 435—439
[52]  [ 32 ] Whitehead J P, Lippard S J. Met. IonsBiol. Sys. , 1996,32: 687—725
[53]  [ 34 ] Kpf H, Kpf-Maier P. Angew. Chem. Int. Ed. Engl. ,1979, 18: 477—481
[54]  [ 35 ] Alessio E, Balducci G, Lutman A , et al. Inorg. Chim.Acta, 1993, 203: 205—217
[55]  [ 36 ] Medicinal Inorganic Chemistry, special issue of Chem.Rev. , 1999, (9)
[56]  [ 37 ] Use of Inorganic Chemistry (ed. Farrell N P). Cambridge:Royal Society of Chemistry, 1999
[57]  [ 38 ] Reviews in Topics in Biological Inorganic Chemistry, Vol.122 (eds. Clarks M J , Sadler P J ). Berlin: Springer-Verlag, 1999
[58]  [ 39 ] Lithium and the Cell: Pharmacology and biochemistry (ed.Birch N J ). London: Academic Press, 1991
[59]  [ 41 ] (a) Price L H, Heninger G R. New Engl. J. Med. , 1994,331: 591; (b) Birch N J. Lithium: Inorganic Pharmacology and Psychiatric Use. Oxford: IRL Press, 1988
[60]  [ 43 ] Clement J L , Jarrett P S. Metal-Based Drugs, 1994, 1:467—482
[61]  [ 46 ] Chen G Q , Shi X G, Tang W , et al. Blood, 1997, 89:3345—3353
[62]  [ 48 ] Mervis J. Science, 1996, 273: 578
[63]  [ 51 ] Best S L , Sadler P J. Gold Bull. , 1996, 29: 87—93
[64]  [ 52 ] Fricker S P. Gold Bull. , 1996, 29: 53—60
[65]  [ 53 ] Shaw C F III. Chem. Rev. , 1999, 99: 2589—2600
[66]  [ 58 ] Menge H, Gregor M , Brosius B, et al. Eur. J. Gastroenterol. Hepatol. , 1994, 4 (S2) : 41—47
[67]  [ 66 ] Sun H, Li H, Harrey I, Sadler P J. J. Biol. Chem. ,1999, 274: 29094—29101
[68]  [ 67 ] Sun H, Li H, Manson A B, et al. J. Biol. Chem. , 2001,276: 8829—8835
[69]  [ 68 ] Kozak R W , Atcher R W , Gansow O A , et al. Proc.Natl. Acad. Sci. USA , 1986, 83: 474—478
[70]  [ 69 ] Chang C A , Francesconi L C, Malley M F, et al. J. Inorg. Chem. , 1993, 32: 3501—3508
[71]  [ 71 ] Inoue Y, Momose T, Ohtake T, et al. J. Nucl. Med. ,1997, 38: 1731—1737

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133