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Cu~(2+)对中华倒刺鲃抗氧化功能的毒理效应

Keywords: Cu~(2+),中华倒刺鲃,超氧化物歧化酶,谷胱甘肽过氧化物酶,毒性

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Abstract:

为了评估重金属污染物对鱼类的毒理效应,利用暴露饲养法研究了短期Cu2+暴露对中华倒刺鲃幼鱼的毒性及其SOD、GSH-Px活性随暴露时间的变化规律。结果表明,Cu2+对中华倒刺鲃幼鱼具有高毒性;低浓度(0.01mg·L-1)Cu2+暴露能诱发SOD、GSH-Px活性升高,但Cu2+浓度升高和暴露时间延长可导致酶活性降低;Cu2+浓度越高,SOD、GSH-Px活性变化越急剧,出现活性抑制的时间就越提前。这些结果表明,Cu2+对中华倒刺鲃抗氧化酶有毒理效应,可通过监测污染水体中鱼类的SOD或GSH-Px活性变化来评估水生生态系统的Cu2+污染程度。

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