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腈醛混合物对明亮发光杆菌联合毒性效应

DOI: 10.11654/jaes.2015.06.005

Keywords: 腈类化合物 醛类化合物 明亮发光杆菌 急性联合毒性 QSAR模型

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Abstract:

选取腈化合物和醛化合物为研究对象, 以明亮发光杆菌为模式生物, 以15 min发光抑制为测定终点, 测定了10种腈醛化合物的单一急性毒性和55组二元非等毒性比腈醛混合体系的联合毒性, 分别建立了腈、醛化合物单一急性毒性的QSAR模型, 并提出了非等毒性比腈醛混合化合物对发光菌联合毒性的QSAR模型。结果表明, 不同的腈醛混合化合物对发光菌的联合毒性不同, 主要呈现协同作用和相加作用。采用QSAR模型定量描述了腈醛类化合物对明亮发光杆菌的联合毒性作用, 为环境介质中腈醛的联合生态风险评价和修复提供了理论依据

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