［3］Dann C E,Hsieh J,Rattner A,et al.Insights into Wnt binding and signaling from the structures of two frizzled cysteine-rich domains[J].Nature,2001,412:86-90.
[4]
［4］Tamai K,Semenov M,Kato Y,et al.LDL-receptor-related proteins in Wnt signal transduction[J].Nature,2000,407:530-535.
[5]
［5］Davidson G,Mao B,del Barco Barrantes I,et al.Kremen proteins interact with dickkopf 1 to regulate anteroposterior CNS patterning[J].Development,2002,129:5 587-5 596.
[6]
［6］Huelsken J,Birchmeier W.New aspects of Wnt signaling pathways in higher vertebrates[J].Curr Opion Genet Dev,2001,11:547-553.
[7]
［7］Dale T C.Signal transduction by the Wnt family of ligands[J].Biochem J,1998,329:209-223.
[8]
［8］Seidensticker M J,Behrens J.Biochemical interactions in the Wnt pathway[J].Biochimica et Biophysica Acta,2000,1 495: 168-172.
[9]
［9］Katoh M,Katoh M.Identification and characterization of human DAMM2 gene in silico[J].Int J Oncol,2003,22: 915-920.
[10]
［10］Yamamoto H,Kishida S,Kishida M,et al.Phosphorylation of axin,a Wnt signal negative regulator,by glycogen syn-thase kinase-3beta regulates its stability[J].J Biol Chem,1999,274:10 681-10 684.
[11]
［11］Zhurinsky J,Shtutman M,Ben-ze′ ev A.Plakoglobin and β-cantenin: protein interactions,regulation and biolo-gical roles[J].J Cell Sci,2000,3 127-3 139.
[12]
［12］Kikuchi A.Roles of axin in the Wnt signaling pathway[J].Cell Signal,1999,11:777-788.
[13]
［13］Meneghini M D,Ishitani T,Carter J.C,et al.MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in caenorhabditis elegans[J].Nature,1999,399:793-797.
