Macek P. Polypeptide cytolytic toxins from sea anemones(Actiniaria) [J]. FEMS Microbiol Immunol, 1992, 5(1-3): 121-129.
[4]
Kem W R. Sea anemone toxins: structure and action[A].Hessinger D A, Lenhoff H M. The biology of Nematocysts[C]. San Diaga: Academic Press, 1988. 375- 405.
[5]
Saier Jr M H. A functional - phylogenetic classification system for transmembrane solute transporters[J]. Microbiol Mol Biol Rev, 2000, 64 (2), 354- 411.
[6]
Jiang X Y, Yang WL, Chen HP, et al. Cloning and characterization of an acidic cytolysin cDNA from sea anemone Sagartia rosea[J]. Toxicon, 2002, 40 (11),1 563- 1 569.
[7]
Anderluh G, Pungercar J, Strukelj B, et al. Cloning, se quencing, and expression of equinatoxin Ⅱ[J ]. Biochem Biophys Res Commun, 1996, 220 (2): 437 - 442.
[8]
Anderluh G, Krizaj I, Strukelj B, etal. Equinatoxins,pore - forming proteins from the sea anemone Actinia equina, belong to a multigene family[J ]. Toxicon, 1999,37 (10): 1391-1401.
[9]
Pungercar J, Anderluh G, Macek P, et al. Sequence analysis of the cDNA encoding the precursor of equinatoxin V, a newly discovered hemolysin from the sea anemone Actinia equina[J]. Biochim Biophys Acta, 1997, 1341(2): 105 - 107.
[10]
Simpson R J, Reid G E, Moritz R L, et al. Complete amino acid sequence of tenebrosin - C, a cardiac stimulatory and haemolytic protein from the sea anemone Actinia tenebrosa[J]. Eur J Biochem, 1990, 190 (2): 319-328.
[11]
Lanio M E, Morera V, Alvarez C, et al. Purification and characterization of two hemolysins from Stichodactyla helianthus[J]. Toxicon, 2001, 39 (2-3): 187-194.
[12]
Monastyrnaia M M, Zykova TA, Kozlovskaia E P. Isolation and characteristics of high molecular weight cytolysins from the sea anemone Radianthus macrodactylus[J ].Bioorg Khim, 1999, 25 (10): 733 - 741.
[13]
Shiomi K, Tanaka E, Yamanaka H, etal. Isolation and characterization of a lethal hemolysin in the sea anemone Parasicyonis actinostoloides[J]. Toxicon, 1985, 23 (5):865 - 874.
[14]
Khoo K S, Kam W K, Khoo H E, et al. Purification and partial characterization of two cytolysins from a tropical sea anemone, Heteractis magnifica[J]. Toxicon, 1993, 31(12): 1567-1579.
[15]
Wang Y, Chua K L, KhHE. A new cytolysin from the sea anenone, Heteractis magnifica: isolation, cDNA cloning and functional expression[J ]. Biochim Biophys Acta, 2000, 1478 (1): 9- 18.
[16]
Bernheimer A W, Lai C Y. Properties of a cytolytic toxin from the sea anemone, Stoichactis kenti[J ]. Toxicon,1985, 23 (5): 791 - 799.
[17]
Macek P, Sencic L, Lebez D. Isolation and partial characterization of three lethal and hemolytic toxins from the sea anemone Actinia cari[J]. Toxicon, 1982, 20 (1):181 - 185.
[18]
Anderluh G, Podlesek Z, Macek P. A common motif in proparts of Cnidarian toxins and nematocyst collagens and its putative role[J]. Biochim Biophys Acta, 2000, 1476(2): 372- 376.
[19]
Anderluh G, Macek P. Cytolytic peptide and protein toxins from sea anemones (Anthozoa: Actiniaria) [J]. Toxicon,2002, 40 (2): 111- 124.
[20]
Valcarcel C A, Dalla Serra M, Potrich C, et al. Effects of lipid composition on membrane permeabilization by sticholysin Ⅰ and Ⅱ, two cytolysins of the sea anemone Stichodactyla helianthus[J]. Biophys J, 2001, 80 (6):2 761 - 2 774.
[21]
Tejuca M, Serra M D, Ferreras M, et al. Mechanism of membrane permeabilization by sticholysin Ⅰ, a cytolysin isolated from the venom of the sea anemone Stichodactyla helianthus[J]. Biochemistry, 1996, 35 (47): 14 947-14 957.
[22]
Hong Q, Gutierrez-Aguirre I, et al. Two- step Membrane Binding by Equinatioxin Ⅰ, a Pore - forming Toxin from the Sea Anemone, Involves an Exposed Aromatic Cluster and a Flexible Helix[J]. J Biol Chem, 2002,277(44) :41 916- 41 924 .
[23]
Anderluh G, Pungercar J, Krizaj I, et al. N-terminal truncation mutagenesis of equinatoxin Ⅰ, a pore - forming protein from the sea anemone Actinia equina [J]. Protein Eng, 1997, 10 (7): 751 - 755.
[24]
Malovrh P, Barlic A, Podlesek Z, et al. Structure-function studies of tryptophan mutants of equinatoxin Ⅰ, a sea anemone pore- forming protein[J]. Biochem J,2000, 15 (346 Pt 1): 223 - 232.
[25]
Anderluh G, Barlic A, Krizaj I, et al. Avidin-FITC topological studies with three cysteine mutants of equina toxin Ⅱ, a sea anemone pore - forming protein[J ].Biochem Biophys Res Commun, 1998, 242 (1):187- 190.
[26]
Anderluh G, Barlic A, Potrich C, etal. Lysine 77is a key residue in aggregation of equinatoxin Ⅱ, a poreforming toxin from sea anemone Actinia equina[J ].J Membr Biol, 2000, 173 (1): 47- 55.
[27]
Mancheno J M, De Los Rios V, Martinez Del Pozo A, et al. Partially folded states of the cytolytic protein sticholysin Ⅱ[J]. Biochim Biophys Acta, 2001, 1545(1-2): 122 -131.
[28]
Caaveiro J M, Echabe I, Gutierrez - Aguirre I, et al.Differential interaction of equinatoxin Ⅱ with model membranes in response to lipid composition [J ]. Biophys J,2001, 80 (3): 1 343- 1 353.
[29]
Athanasiadis A, Anderluh G, Macek P, et al. Crystal structure of the soluble form of equinatoxin Ⅱ, a poreforming toxin from the sea anemone Actinia equina [J ].Structure, 2001, 9 (4): 341-346.
[30]
Menestrina G, Cabiaux V, Tejuca M, et al. Secondary structure of sea anemone cytolysins in soluble and membrane bound form by infrared spectroscopy[J]. Biochem Biophys, 1999, 254 (1): 174 -180.
[31]
Huerta V, Morera V, Guanche Y, et al. Primary structure of two cytolysin isoforms from Stichodactyla helianthus differing in their hemolytic activity[J]. Toxicon, 2001,39 (8): 1 253 - 1 256.
[32]
Anderluh G, Barlic A, Podlesek Z, et al. Cysteinescanning mutagenesis of an eukaryotic pore - forming toxin from sea anemone: topology in lipid membranes[J]. Eur J Biochem, 1999, 263 (1): 128-136.
[33]
赵铁华 施波 等.RGD和YIGSR衍生物的抗肿瘤侵袭、转移活性[J].肿瘤,:.
[34]
Martin - Benito J, Gavilanes F, de Los Rios V, et al.Two - dimensional crystallization on lipid monolayers and three - dimensional stucture of sticholysin Ⅱ, a cytolysin from the sea anemone Stichodactyla helianthus [J]. Biophys J, 2000, 78 (6): 3 186 - 3 194.
[35]
Poklar N, Fritz J, Macek P, et al. Interaction of the pore -forming protein equinatoxin Ⅱ with model lipid membranes: A calorimetric and spectroscopic study[J ].Biochemistry, 1999, 38 (45): 14 999 - 15 008.
[36]
Belmonte G, Pederzolli C, Macek P, et al. Pore formation by the sea anemone cytolysin equinatoxin Ⅱ in red blood cells and model lipid membranes[J]. J Membr Biol,1993, 131 (1): 11-22.
[37]
Bunc M, Drevensek G, Budihna M, et al. Effects of equinatoxin Ⅱ from Actinia equina (L.) on isolated rat heart: the role of direct cardiotoxic effects in equinatoxinⅡ lethality[J]. Toxicon, 1999, 37 (1): 109 -123.
[38]
Drevensek G, Budihna MV, Suput D, et al. Nicardipine dose - dependently reduces the effect of equinatoxin Ⅱ on coronary flow in isolated porcine heart[J]. Pflugers Arch, 2000, 440 (5 Suppl): R145 - 146 .
[39]
Suput D, Frangez R, Bunc M. Cardiovascular effects of equinatoxin Ⅲ from the sea anemone Actinia equina (L.)[J]. Toxicon, 2001, 39 (9): 1 421 - 1 427.
[40]
Batista U, Jezernik K. Morphological changes of V- 79cells after equinatoxin Ⅱ treatment[J ]. Cell Biol, 1992,16 (2): 115 - 123.
[41]
Khoo HE, Lim J P, Tan CH. Effects of sea anemone(Heteractis magnifica and Actinia equina) cytolysins on synaptosomal uptake of GABA and choline[J]. Toxicon,1995, 33 (10): 1 365- 1 371.
[42]
Migues P V, Leal R B, Mantovani M, et al. Synaptosomal glutamate release induced by the fraction Bc2 from the venom of the sea anemone Bunodosona caissarum[J ].Neuroreport, 1999, 10 (1): 67- 70.
[43]
Tejuca M, Anderluh G, Macek P, et al. Antiparasite activity of sea - anemone cytolysins on Giardia duodenalis and specific targeting with anti- Giardia antibodies[J].Iht J Parasitol, 1999, 29 (3): 489 - 498.
[44]
Pederzolli C, Belmonte G, Dalla Serra M, et al.Biochemical and cytotoxic properties of conjugates of tansferrin with equinatoxin Ⅱ, a cytolysin from a sea anemone[J]. Bioconjug Chem, 1995, 6 (2): 166 -173.
[45]
Zorec R, Tester M, Macek P, et al. Cytotoxicity of equinatoxin Ⅱ from the sea anemone Actinia equina involves ion channel formation and an increase in intracellular calcium activity[J]. J Membr Biol, 1990, 118(3):243-249.