Vidyadagar J, Karunakar N, Reddym S, et al. Oxidative stress and antioxidant status in acute organophosphorous insecticide poisoning[J]. Indian 3 Pharmaeol, 2004, 36(2): 76-79.
[3]
Blasiak J , Jaloszynski P , Trzeciak A , et al. In vitro studies on the enotoxicity of the rganophosphorus insecticide malathion and its two analogues[J]. Mutation Research, 1999, 445(2): 275-283.
[4]
Dedek W, Grahl R, Schmidt R. A comparative study of guanine N7-alkylation in mice in vivo by the organophosphorus insecticides trichlorphon, dimethoate, phosmet and bromophos[J]. Acta Pharm Toxicol, 1984, 55(2): 104-109.
[5]
Mehl A, Rolseth V , Gordon S. Brain hypoplasia caused by exposure to trichlorfon and dichlorvos during development can be ascribed to DNA alkylation damage and inhibition of DNA alkyltransferase repair[J]. Neurotoxieol, 2000, 21(122): 165-173.
Evenson D P, Jost L K, Gandy J. Glutathione depletion potentiates ethyl methanesulfonate -induced damage to sperm chromatin structure[J]. Reprod Toxicol, 1993, 7: 297-304.
[9]
Wild D. Mutagenicity studies on organophosphorus pesticide[J]. Mutat Res, 1975, 32: 133-137.
[10]
Bolognesi C. Genotoxicity of pesticides: a review of human biomonitoring studies[J]. Mutation Research, 2003,543(3): 251-272
[11]
Sukran C, Rabia S. Genotoxicity testing of some organophosphate insecticides in the Drosophila wing spot test[J]. Food and Chemical Toxicology, 2005, 43: 443-450.
[12]
刘玉清 胡渝华.有机磷农药在DNA重组修复试验中的诱变性研究[J].现代预防医学,:.
[13]
Moriya M , Ohta T , Watanabe K , et al. Further mutagenicity studies on pesticides in bacterial reversion assay systems [J]. Mutat Res, 1983, 116 (3-4): 185-216
[14]
Cho T H , Wild J R , Donnelly K C. Utility of organophosphorus hydrolase for the remediation of mutagenicity of methyl parathion[J]. Environ Toxieol Chem, 2000, 19 (8): 2022-2028.
[15]
Das P, John G. Induction of sister chromatid exchanges and chromosome aberrations in vivo in Etroplus suratensis (Bloch) following exposure to organophosphorus pesticides[J]. Toxicol Lett, 1999, 104(1/2): 111-116
[16]
Zahran M M, Abdel A K B, Abdel R A, et al. The effect of subacute doses of organophosphorus pesticide, nuvacron, on the biochemical and cytogenetic parameters of mice and their embryos[J]. Research Journal of Agriculture and Biological Sciences, 2005, 1(3): 277-283.
[17]
Wang T C , Lin C M , Lo L W. Genotoxicity of methoxyphosphinyl insecticide in mammalian cells[J]. Zool Stud, 2003, 42(3): 462-469.
[18]
Jena B. Mutagenicity of an organophosphate insecticide acephate-an in vivo study in chicks[J]. Mutagenesis, 1994, 9: 319-324.
[19]
Tolga C , Serpil K. Detection of cytogenetic and DNA damage in peripheral erythrocytes of goldfish (Carassius auratus) exposed to a glyphosate formulation using the micronucleus test and the comet assay[J]. Mutagenesis, 2007, 12: 1-6.
[20]
Saleha B B, Danadevi K, Rahman M F, et al. Genotoxic effect of monocrotophos to sentinel species using comet assay[J]. Food Chem Toxicol, 2001, 39(4): 361-366.
[21]
Undeger U , Basaran N . Effects of pesticedes on human peripheral lymphocytes in vitro: induction of DNA damage[J]. Arch Toxicol, 2005, 79: 169-176.
[22]
Rahman M F , Mahboob M , Danadevi K , et al Assessment of genotoxic effects of chloropyriphos and acephate by the comet assay in mice leucocytes[J]. Mutation Research, 2002, 516:139-147
[23]
Sushila Patel, Mahima Bajpayee, Alok Kumar Pandey, et al. In vitro induction of cytotoxicity and DNA strand breaks in CHO cells exposed to cypermethrin, pendimethalin and dichlorvos[J]. Toxicology in Vitro, 2007, 21:1 409-1 418.
[24]
Padungtod C , Hassold T J , Elise Millie, et al. Sperm aneupioidy among Chinese pesticide factory workers: Scoring by the FISH method[J]. American Journal of Industrial Medicine, 1999, 36(2): 230-238.
[25]
王硕治.[D].中国海洋大学,2008.
[26]
Domenech C E, Machado de Domenech E E, Balegno H F,et al. Pesticide action and membrane fluidity. Allosteric behavior of rat erythrocyte membrane-bound acetylcho- linesterase in the presence of organophosphorous compounds[J]. FEBS Lett, 2000, 74:243-246
[27]
Sharma Y , Bashir S , Irshad M, et al. Effects of acute dimethoate administration on antioxidant status of liver and brain of experimental rats[J]. Toxieol, 2005, 206: 49-57.
[28]
Gultekin F , Ozturk M , Akdogan M . The effect of organophosphate insecticide chlorpyrifos-ethyl on lipid peroxidation and antioxidant enzymes (in vitro)[J]. Arch Toxieol, 2000, 74: 533-538.
[29]
Ranjbar A , Pasalar P , Abdollahi M. Induction of oxidative stress and acetylcholinesterase inhibition in organophosphorous pesticide manufacturing workers[J]. Hum Exp Toxieol, 2002, 21: 179-182.
[30]
Nackerdien Z, Rao G, Cacciuttolo M A nature of mammalian DNA-protein chromatin by cross-links et al. Chemical produced in hydrogen peroxide in the presence of iron or copper ions[J]. Biochemistry, 1991 30:4 873-4 879
[31]
Hughes C M, Lewis S E, McKelvey-Martin V J , et al. Acomparison of baseline and induced DNA damage in human spermatozoa from fertile and infertile men, using a modified comet assay[J]. Mol Hum Reprod , 1996, 2: 613-619.
[32]
Dizdaroglu M, Nackerdien Z, Chao B C, et al. Chemical nature of in vivo DNA base damage in hydrogen peroxide-treated mammalian cells[J]. Arch Biochem Biophys, 1991, 285: 388-390.
[33]
Emerit I. Reactive oxygen species, chromosome mutation, and cancer: possible role of clastogenic factors in carcinogenesis[J]. Free Radical Biol Med, 1994, 16: 99-109.
[34]
Pina-Guzman B , Solis-Heredia M J, Rojas-Garcia A E, et al. Genetic damage caused by methyl-parathion in mouse spermatozoa is related to oxidative stress[J]. Toxicol Appl Pharm, 2006, 216:216-224.
[35]
Bagchi D, Bagchi M, Hassoun E A, et al. In vitro and in vivo generation of reactive oxygen species, DNA damage and lactate dehydrogenase leakage by selected pesticides [J].Toxicology, 1995, 104: 129-140.
[36]
Fu Yu, Ziren Wang, Bao Ju, et al. Apoptotic effect of organophosphorus insecticide chlorpyrifos on mouse retina in vivo via oxidative stress and protection of combination of vitamins C and E[J]. Experimental and Toxicologic Pathology, 2008, 59:415-523
[37]
Kovacic P. Mechanism of organophosphates ( nerve gases and pesticides) and antidotes: electron transfer and oxidative stress[J]. Curr Med Chem, 2003, 10:2 705- 2 709.
[38]
Bondy S C, Naderi S. Contribution of hepatic cytochrome P450 systems to the generation of reactive oxygen species [J]. Biochem Pharmacol, 1994, 48: 155-159.
Pina G B, Solis H M J,Rojas G A E,et al. Diazinon alters sperm chromatin structure in mice by phosphorylating muclear protamines[J]. Toxicology and Applied Pharmacology, 2005, 202:189-198.
