［1］Searle A G. Comparative genetics of albinism. Ophthalmic Paediatr Genet, 1990,11(3): 159- 164
[2]
［2］Nakamura K, Ozaki A, Akutsu T,et al. Genetic mapping of the dominant albino locus in rainbow trout (Oncorhynchus mykiss). Mol Genet Genomics, 2001, 265(4): 687- 693
[3]
［3］Kajishima T, Takeuchi I K. Ultrastructural analysis of gene interaction and melanosome differentiation in the retinal pigment cell of the albino goldfish. J Exp Zool, 1977, 200 (3):349- 357
[4]
［4］Inagaki H, Koga A. The tyrosinase gene from medakafish: transgenic expression rescues albino mutation. Pigment Cell Res, 1998, 11(5): 283- 290
[5]
［5］Koga A, Inagaki H, Bessho Y, et al. Insertion of a novel transposable element in the tyrosinase gene is responsible for an albino mutation in the medaka fish, Oryzias latipes. Mol Gen Genet, 1995, 249(4): 400- 405
[6]
［6］Koga A, Wakamatsu Y, Kurosawa J, et al. Oculocutaneous albinism in the i6 mutant of the medaka fish is associated with a deletion in the tyrosinae gene. Pigment Cell Res, 1999, 12 (4): 252- 258
[7]
［7］Hyodo- Tagushi Y, Winkler C, Kurihara Y, et al. Phenotypic rescue of the albino mutation in the medakafish(Oryzias latipes) by a mouse tyrosinase transgene. Mechanisms of Development, 1997, 68(1- 2): 27- 35
[8]
［8］Inagaki H, Bessho Y, Koga A,et al. Expression of the tyrosinase- encoding gene in a colorless melanophore mutant of the medaka fish, Oryzias latipes. Gene, 1994, 150:319- 324
[9]
［9］Inagaki H, Koga A. The tyrosinase gene from medakafish: transgenic expression rescues albino mutation. Pigment Cell Res, 1998, 11(5): 283- 290
[10]
［10］Lijuan Fu, Mambrini M. Stable and full rescue of the pigmentation in a medaka albino mutant by transfer of a 17kb genomic clone containing the medaka tyrosinase gene. Gene, 2000, 241: 205- 211
[11]
［11］Eun- Jung Jin, Giselle T. Effect of lithium on pigmentation in the embryonic zebrafish (Brachydanio rerio). Biochemica et Biophysica Acta, 1999, 1449: 93- 99
[12]
［12］Kelsh R N, Schmid B. Genetic analysis of melanophore development in zebrafish embryos. Dev Biol, 2000, 225: 277- 293
[13]
［13］Estevez A, McEvoy L A, Bell J G,et al. Growth, survival, lipid composition and pigmentation of turbot larvae fed live- prey enriched in arachidonic and eicosapentaenoic acids. Aquaculture, 1999, 180(3/4): 321- 343
[14]
［14］Estevez A, Kanazawa A. Effect of (n- 3) PUFA and Vitamin A Artemia enrichment on pigmentation success of turbot, Scophthalmus maximus. Aquaculture Nutrition(United Kingdom), 1995, 1(3): 159- 168
［16］Sanchez- Amat A, Lucas- Elio P, Fernandez E. Molecular cloning and functional characterization of a unique multipotent polyphenol oxidase from Marinomonas mediterranea. Biochemica et Biophysica Acta, 2001, 154: 104- 116
[17]
［17］Halaban R, Cheng E. Aberrant retention of tyrosinase in the endoplasmic reticulum mediates accelerated degradation of the enzyme and contributes to the dedifferertiated phenotype of amelanotic melanoma cells. Proc Natl Acad Sci USA, 1997, 94(12): 6 210- 6 215
[18]
［18］Halaban R, Svedine S, Cheng E, et al. Endoplasmic re- ticulum retention is a common defect associated with tyrosinase- negative albinism. Proc Natl Sci USA, 2000, 97 (11): 5 889- 5 894
[19]
［19］Rinchik E M, Bultman S J, Horsthemke B, et al. A gene for the mouse pink- eyed dilution locus and for human type II oculocutaneous albinism. Nature, 1993, 361:72- 76
[20]
［20］Potterf S B, Furumura M, Sviderskaya E V,et al. Normal tyrosinase transport and abnormal tyrosinase routing in pinked- eyed dilution melanocytes. Experimental Cell Research ,1998, 244: 319- 326
[21]
［21］Puri N, Gardner J M, Brilliant M H. Aberrant pH of melanosomes in pink- eye dilution(p) mutant melanocytes. J Invest Dermatol, 2000, 115, 607- 613
[22]
［22］Fuller B B, Spaulding D T, Smith D R,et al. Regulation of the catalytic activity of pre- existing tyrosinase in black and Caucasian human melanocyte cell cultures. Exp Cell Res, 2001,262: 197- 208
[23]
［23］Halaban R, Cheng E, Svedine S, et al. Proper folding and endoplasmic reticulum to Golgi transport of tyrosinase are induced by its substrates, dopa and tyrosine. The Journal of Biological Chemistry, 2001, 15: 11 933- 11 938
[24]
［24］Richard A. Human pigmentation genes:identification, structure and consequences of polymorphic variation. Gene, 2001, 277: 49- 62
[25]
［25］Oetting W S. The tyrosinase gene and oculocutaneous albinism type 1(OCA1): A model for understanding the molecular biology of melanin formation. Pigment Cell Res, 2000, 13 (5):320- 325
[26]
［26］Koga A, Hori H. Albinism due to transposable element insertion in fish. Pigment Cell Res, 1997, 10(6): 377- 381
[27]
［27］Hori H, Suzuki M, Inagaki H, et al. An active Ac- like transposable element in teleost fish. Journal of Marine Biotechnology, 1998, 6(4): 206- 207
[28]
［28］Bolker J A, Hill C R. Pigmentation development in hatch- ery- reared flatfishes. Journal of Fish Biology, 2000, 56(5): 1 029- 1 052
