［1］Sekiguchi K, Yamamichi Y, Seshimo H, et al. Biology of Horseshoe Crabs[M]. Tokyo: Science House, 1988.
[2]
［2］Iwanaga S. The molecular basis of innate immunity in the horseshoe crab[J]. Curr Opin Immunol, 2002,14(1): 87- 95.
[3]
［3］Iwanaga S, Kawabata S. Evolution and phylogeny of defense molecules associated with innate immunity in horseshoe crab[J]. Front Biosci, 1998,3:973- 984.
[4]
［4］Muta T, Iwanaga S. The role of hemolymph coagulation in innate immunity[J]. Curr Opin Immuno, 1996,8:41- 47.
[5]
［5］Muta T, Iwanaga S. Clotting and immune defense in Limulidae[J]. Prog Mol Subcell Biol, 1996,15:154- 189.
[6]
［6］Ding J L, Ho B. A new era in pyrogen testing[J]. Trends Biotech, 2001,19(8):277- 281.
[7]
［7］Takaki Y, Seki N, Kawabata S S, et al. Duplicated binding sites for (1→ 3)- beta- D- glucan in the hor- seshoe crab coagulation factor G: implications for a molec- ular basis of the pattern recognition in innate immunity[J]. J Biol Chem, 2002,277(16):14 281- 14 287.
[8]
［8］Gokudan S, Muta T, Tsuda R, et al. Horseshoe crab acetyl group- recognizing lectins involved in innate im- munity are structurally related to fibrinogen[J]. Proc Natl Acad Sci USA, 1999,96(18):10 086- 10 091.
[9]
［9］Kawabata S, Iwanaga S. Role of lectins in the innate immunity of horseshoe crab[J]. Develop Compara Immuno, 1999,23(4- 5):391- 400.
[10]
［10］Kawabata S, Tsuda R. Molecular basis of non- self re- cognition by the horseshoe crab tachylectins[J]. Biochim Biophys Acta, 2002,1 572:414- 421.
[11]
［11］Matsuzaki K. Why and how are peptide- lipid interactions utilized for self- defense? Magainins and tachyplesins as archetypes[J]. Biochim Biophys Acta, 1999,1 462(1- 2):1- 10.
[12]
［12］Matsuzaki K, Yoneyama S, Fujii N, et al. Membrane permeabilization mechanisms of a cyclic antimicrobial peptide tachyplesin I, and its linear analog[J]. Bioche- mistry, 1997,36(32):9 799- 9 806.
[13]
［13］Chen Y X, Xu X M, Hong S G, et al. RGD- tachyplesin inhibits tumor growth[J]. Cancer Res, 2001,61(6): 2 434- 2 438.
[14]
［14］Suetake T, Tsuda S, Kawabata S, et al. Chitin- binding proteins in invertebrates and plants comprise a common chitin- binding structural motif[J]. J Biol Chem, 2000, 275(24):17 929- 17 932.
[15]
［15］Osaki T, Omotezako M, Nagayama R, et al. Horseshoe crab hemoyte- derived antimicrobial polypeptides, tachystatins, with sequence similarity to spider neurotoxins[J]. J Biol Chem, 1999,274(37):26 172- 2 6178.
[16]
［16］Fujitani N, Kawabata S, Osaki T, et al. Structure of the antimicrobial peptide tachystatin A[J]. J Biol Chem, 2002,277(26):23 651- 23 657.
[17]
［17］Kawabata S, Saito T, Saeki K, et al. cDNA cloning, tissue distribution, and subcellular localization of horseshoe crab big defensin[J]. Biol Chem, 1997,378(3- 4): 289- 292.
[18]
［18］Iwanaga S, Kawabata S, Muta T. New types of clotting factors and defense molecules found in horseshoe crab hemolymph: their structure and functions[J]. J Biochem, 1998,123(1):1- 15.
