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海洋科学  2009 

黄鳍金枪鱼巨噬细胞移动抑制因子(MIF)的克隆与序列分析

, PP. 29-34

Keywords: 黄鳍金枪鱼(Thunnus,albacares),巨噬细胞移动抑制因子(MIF),分子克隆,序列分析

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Abstract:

采用同源克隆的方法、利用RACE技术从黄鳍金枪鱼(Thunnusalbacares)肝脏中克隆了其MIF(TaMIF)的cDNA序列。TaMIF的cDNA全长706bp含一个345bp的开放阅读框,编码一个长115氨基酸的蛋白质。信号肽预测分析表明TaMIF没有信号肽。序列分析与进化分析表明,黄鳍金枪鱼与近海养殖鱼类MIF的氨基酸序列高度相似、进化地位相近,预示着深海鱼类TaMIF与近海养殖鱼类具有相似的生物学功能。研究结果是对深海鱼类MIF基因信息资料的重要补充。

References

[1]  Kleemann R,Rorsman H,Rosengren E,Dissection of the enzymatic and immunologic functions of macrophage migration inhibitory factor.Full immunologic activity of N-terminally truncated mutants,Ear J Biochem,2000(24).
[2]  Sato A,Uinuk-ool T S,Kuroda N,Macrophage migration inhibitory factor(MIF)of jawed and jawless fishes:implications for its evolutionary origin,Developmental and Comparative Immunology,2003(05).
[3]  Miska K B,Fetterer R H,Lillehoj H S,Characterisation of macrophage migration inhibitory factor from Eimeria species infectious to chickens,Molecular and Biochemical Parasitology,2007(02).
[4]  Kleemann R,Hausser A,Geiger G,Intracellu-lar action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jabl,Nature,2000.
[5]  Kleemann R,Kapurniotu A,Frank R W,Disulfide analysis reveals a role for macrophage migration inhibitory factor(MIF)as thiol-protein oxidoreduetase,Journal of Molecular Biology,1998(01).
[6]  Calandra T,Roger T,Macrophage migration inhibitory factor:a regulator of innate immunity,Nature Reviews Immunology,2003(10).
[7]  Weiser W Y,Temple P A,Witek-Giannotti J S,Molecular cloning of a cDNA encoding a human macrophage migration inhibitory factor,Proceedings of the National Academy of Sciences(USA),1989(19).
[8]  Bernhagen J,Calandra T,Mitchell R A,MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia,Nature,1993(6448).
[9]  Roger T,David J,Glauser M P,MIF regulates innate immune responses through modulation of Tolllike receptor 4,Nature,2001(6866).
[10]  Roger T,Froidevaux C,Martin C,Macrophage migration inhibitory factor(MIF)regulates host responses to endotoxin through modulation of Toll-like receptor 4(TLR4),Journal of Endotoxin Research,2003(02).
[11]  Stosic-Grujicic S,Stojanovic I,Nicoletti F,MIF in autoimmunity and novel therapeutic approaches,Aytimmun Rev,2008.
[12]  金红建.邵健忠.项黎新 红鳍东方纯MIF基因的鉴定及生物信息学分析 [J].-水生生物学报2007(01)
[13]  Ito K,Yoshiura Y,Ototake M,Macrophage migration inhibitory factor(MIF)is essential for development of zebrafish,Danio rerio,Developmental and Comparative Immunology,2008(06).
[14]  Jin Hong-jian,Xiang Li-xin,Shao Jian-zhong,Molecular cloning and identification of macrophage migration inhibitory factor(MIF)in teleost fish,Developmental and Comparative Immunology,2007(11).
[15]  孟晓梦.叶振江.王英俊 世界黄鳍金枪鱼渔业现状和生物学研究进展 [J].-南方水产2007(04)

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